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NCT03426722
L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors
Phase 3 trial testing L-carnitine in Gastrointestinal Stromal Tumors (GISTs) in 4 participants. Completed in 24 December 2019.
24 December 2019
Quick facts
| Lead sponsor | Asan Medical Center |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 4 |
| Start date | 1 March 2018 |
| Primary completion | 24 December 2019 |
| Estimated completion | 24 December 2019 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- L-carnitine — full drug profile →
- Placebo
Conditions studied
- Gastrointestinal Stromal Tumors (GISTs) — all drugs for Gastrointestinal Stromal Tumors (GISTs) →
Sponsor
Asan Medical Center
Who can join
18 and older, any sex, with Gastrointestinal Stromal Tumors (GISTs). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
we aim to evaluate the efficacy of L-carnitine for the treatment of muscle cramps after imatinib in patients with GIST and apply in the future.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Impact of L-carnitine on imatinib-related muscle cramps in patients with gastrointestinal stromal tumor.
Chae H, Ryu MH, Ma J, Beck M, et al · · 2020 · cited 5× · PMID 31628586 · DOI 10.1007/s10637-019-00860-x
Verify or expand the search:
- PubMed search for NCT03426722
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of L-carnitine
Trials testing the same drug.
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- NCT06960694 — Effect of L-carnitine on Disease Activity in Patients With Mild to Moderate Knee Osteoarthritis · Phase 2 · completed
- NCT06901323 — Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Child · Phase 4 · active not recruiting
- NCT05355311 — Enhancing the Effects of Alcohol Treatment With L-Carnitine · Phase 1 · completed
Other Asan Medical Center trials
Trials by the same sponsor.
- NCT07530393 — Blood Viscosity and Outcomes After Elective Craniotomy · not yet recruiting
- NCT07010497 — A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Be · Phase 2 · recruiting
- NCT07382505 — Prospective Cohort Study of Minimal Residual Disease(MRD) Testing for Early Recurrence Detection in Endometrial and Cerv · not yet recruiting
- NCT07489092 — Feasibility of a Digital Rehabilitation Platform in Patients After ICU Discharge · NA · recruiting
- NCT07431762 — Comparison of Anti-Thrombotic Treatments Between Aspirin and Warfarin During Initial Six Months After Bioprpsthetic Hear · Phase 4 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03426722 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Asan Medical Center
- Last refreshed: 13 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03426722.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing