Last reviewed · How we verify
NCT03419702
Almonds and Health Effects on Metabolism, Vascular Function and Cognition
NA trial testing Almonds in PreDiabetes in 43 participants. Completed in 3 December 2021.
3 December 2021
Quick facts
| Lead sponsor | Maastricht University Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 43 |
| Start date | 10 January 2018 |
| Primary completion | 3 December 2021 |
| Estimated completion | 3 December 2021 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Almonds
Conditions studied
- PreDiabetes — all drugs for PreDiabetes →
- Impaired Glucose Tolerance — all drugs for Impaired Glucose Tolerance →
- Impaired Fasting Glucose — all drugs for Impaired Fasting Glucose →
- Overweight and Obesity — all drugs for Overweight and Obesity →
Sponsor
Maastricht University Medical Center
Who can join
Adults 40 to 70, any sex, with PreDiabetes or Impaired Glucose Tolerance. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary objective of the proposed study is to examine and understand the impact of long-term almond consumption on chronic glucose metabolism in subjects with impaired glucose tolerance and/or impaired fasting glucose.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The effects of long-term almond consumption on whole-body insulin sensitivity, postprandial glucose responses, and 48 h continuous glucose concentrations in males and females with prediabetes: a randomized controlled trial.
Gravesteijn E, Mensink RP, Plat J. · · 2023 · cited 10× · PMID 37258943 · DOI 10.1007/s00394-023-03178-w -
Effects of long-term almond consumption on markers for vascular function and cardiometabolic risk in men and women with prediabetes: results of a randomized, controlled cross-over trial.
Chavez-Alfaro MA, Mensink RP, Gravesteijn E, Joris PJ, et al · · 2024 · cited 3× · PMID 39546040 · DOI 10.1007/s00394-024-03510-y
Verify or expand the search:
- PubMed search for NCT03419702
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Almonds
Trials testing the same drug.
- NCT05782218 — Healthy Unique Lipids From Almonds · NA · completed
- NCT04958018 — Almond Supplementation and Exercise Recovery · NA · completed
- NCT04778371 — The Effects of Almond Consumption on Functional Performance and Activity in Overweight Active Older Adults · NA · active not recruiting
- NCT04223323 — Effects of Almond Consumption on the Human Gastrointestinal Microbiota and Metabolic Health · NA · completed
- NCT04243395 — Protein Source on Plasma Amino Acid Concentrations In Older Adults · NA · completed
Other recruiting trials for PreDiabetes
Currently open trials in the same condition.
- NCT06897982 — Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center · NA · recruiting
- NCT06967558 — The Role of Islet GLP-1 in the Pathogenesis of Prediabetes · Phase 2 · recruiting
- NCT06482944 — Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes · NA · recruiting
- NCT06989164 — Post Prandial Individual Responses to Different Foods · NA · recruiting
- NCT07254572 — Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes · Phase 4 · recruiting
Other Maastricht University Medical Center trials
Trials by the same sponsor.
- NCT04603261 — Time to Excretion of Contrast, a Maastricht Prospective Observational Study · withdrawn
- NCT04598516 — Maastricht Investigation of Renal Function in Absence of- and Post- Contrast in Patients With eGFR LEss Than 30 · withdrawn
- NCT04597892 — Efficacy of Point-Of-Care Creatinine Assays in Patients With eGFR <30 Receiving Intravascular Contrast · withdrawn
- NCT07287358 — Optimal Cerebral Perfusion Pressure Guided Therapy: Assessment of Target Effectiveness - II · NA · not yet recruiting
- NCT07501780 — Real-world Evaluation of the Implementation of LC-OCT in Daily Clinical Practice · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03419702 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Maastricht University Medical Center
- Last refreshed: 4 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03419702.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing