Last reviewed · How we verify
NCT03403023
Corneal Tear Film Imaging of the Cornea Before and After Restasis Therapy
NA trial testing Tear Film Imager in Dry Eye Syndrome in 40 participants. Status unknown.
30 May 2018
Quick facts
| Lead sponsor | Meir Medical Center |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 40 |
| Start date | 30 January 2018 |
| Primary completion | 30 May 2018 |
| Estimated completion | 30 December 2018 |
Drugs / interventions tested
- Tear Film Imager
- Restasis — full drug profile →
Conditions studied
- Dry Eye Syndrome — all drugs for Dry Eye Syndrome →
- Tear Film Insufficiency — all drugs for Tear Film Insufficiency →
Sponsor
Meir Medical Center
Who can join
18 and older, any sex, with Dry Eye Syndrome or Tear Film Insufficiency. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dry Eye Syndrome (DES) is a disease affects the production and stability of the tear film, leading to vision disturbances and a major decrease in quality of life. The most recommended treatment for moderate-severe DES today which failed conservative therapy with lubricating eye drops is topical Cyclosporine 0.05% (Restasis®). The Tear Film Imager (TFI) is a novel imaging modality designed for visualization of the individual tear film layers up to a resolution of 0.1 micrometers, a property not enabled by any other imaging modality for this indication to date. In this study we wish to assess the effects of topical Cyclosporine 0.05% on the tear film using the TFI. In our previous study we found this modality yields high resolution images of the tear film, yielding significant differences between healthy and diseased (DES) eyes. We believe the TFI will improve quality of assessment and follow-up of DES patients, allowing more effective diagnosis and treatment of this disease in the future.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03403023
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Tear Film Imager
Trials testing the same drug.
- NCT04670263 — Evaluating the Efficacy of Dry Eye (DE) Disease Treatment Using Novel Tear Film Imager (TFI) · Phase 2, PHASE3 · completed
- NCT03061578 — Evaluation of Dry Eye by Tear Film Imager in a Low Humidity Environmental Exposure Chamber (TFI-LH16) · completed
Other recruiting trials for Dry Eye Syndrome
Currently open trials in the same condition.
- NCT07295691 — Autologous Serum Eye Drops in Dry Eye Syndrome · NA · recruiting
- NCT06914232 — Efficacy of Warm Compress Therapy in Enhancing Tear Film Quality and Reducing Postoperative DES · NA · active not recruiting
- NCT06913556 — Comparing Effect of Hylorunic Acid and Lipid-coated Carbomer Gel on Dry Eyes After Phacoemulsification in DP · NA · active not recruiting
Other Meir Medical Center trials
Trials by the same sponsor.
- NCT07256886 — Validation of the iCVS Model in Patients Admitted to the Intensive Care Unit · not yet recruiting
- NCT07315477 — Characteristics of Patients Intubated for Airway Protection in the Intensive Care Unit and Timing of Tracheostomy · not yet recruiting
- NCT07183410 — Impact of Blood Cultures Drawn From Arterial Lines on the Incidence of Contamination, Detection of Bacteremia, and Blood · not yet recruiting
- NCT07256860 — Influence of Chest X-ray vs. Chest CT Scan on the Management of ICU Patients With Respiratory Failure · not yet recruiting
- NCT05784350 — Preoperative Point of Care Ultrasound Guided Fluid Optimization and Intravenous Ondansetron to Prevent General Anesthesi · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03403023 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Meir Medical Center
- Last refreshed: 18 January 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03403023.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing