Last reviewed · How we verify
NCT07256886
Validation of the iCVS Model in Patients Admitted to the Intensive Care Unit
trial in Shock in 1,150 participants. Not yet recruiting.
1 April 2030
Quick facts
| Lead sponsor | Meir Medical Center |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 1,150 |
| Start date | 1 April 2026 |
| Primary completion | 1 April 2030 |
| Estimated completion | 30 April 2030 |
Conditions studied
- Shock — all drugs for Shock →
Sponsor
Meir Medical Center
Who can join
18 and older, any sex, with Shock. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
One of the significant challenges in the care of critically ill patients in the intensive care unit is the assessment of hemodynamically unstable patients (shock states). The treating team uses data such as heart rate, arterial blood pressure, physical examination findings, etc. to assess the patient's cardiac output, peripheral vascular resistance, filling pressures and volumes, and vascular tone. These assessments are essential to assess the cause of shock (cardiac cause, hypovolemia, sepsis, etc.), but in many situations they are not easy to perform and require extensive knowledge and experience. Assessing the hemodynamic status of a critically ill patient based on dynamic mechanical models may be a good option for more accurate assessment of complex patients. Such a model is, for example, the iCVS model: it is a relatively simple, mechanical-dynamic model that can be used to understand complex cardiovascular conditions. This model requires only age and weight as initial data, and as dynamic data the model requires only an arterial blood pressure (AR) curve and a central venous pressure (CVP) curve. The model is based on the shape of the above curves for the purpose of analyzing the cardiovascular status of the patient. The model is suitable for both adults and children, although most of the work to date has been among pediatric intensive care patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07256886
- Europe PMC full search
- ASCO Meeting Library
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- bioRxiv preprints
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Other Meir Medical Center trials
Trials by the same sponsor.
- NCT07315477 — Characteristics of Patients Intubated for Airway Protection in the Intensive Care Unit and Timing of Tracheostomy · not yet recruiting
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- NCT07256860 — Influence of Chest X-ray vs. Chest CT Scan on the Management of ICU Patients With Respiratory Failure · not yet recruiting
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- NCT06929494 — Candidemia in Critically Ill Patients · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07256886 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Meir Medical Center
- Last refreshed: 1 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07256886.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing