NCT03388463 is a NA clinical trial of Omeprazole in Critical Illness, sponsored by Menoufia University.

Who is sponsoring NCT03388463?

NCT03388463 is sponsored by Menoufia University.

What drugs are being tested in NCT03388463?

Interventions in NCT03388463: Omeprazole, Placebo group.

What condition does NCT03388463 study?

NCT03388463 studies Critical Illness.

Is NCT03388463 still recruiting?

NCT03388463 is currently completed. Last updated 3 January 2018.

Last reviewed 2018-01-03 · How we verify

NCT03388463

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Single Dose Omeprazole Versus High Dose in High-risk Critically Ill Patients.

Completed NA Last updated 3 January 2018

What this trial tests

NA trial testing Omeprazole in Critical Illness in 110 participants. Completed in 17 September 2017.

Timeline

11 May 2016

Primary endpoint
14 August 2017

17 September 2017

Quick facts

Lead sponsor	Menoufia University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	prevention
Enrollment	110
Start date	11 May 2016
Primary completion	14 August 2017
Estimated completion	17 September 2017

Drugs / interventions tested

Omeprazole (omeprazole) — full drug profile →
Placebo group

Conditions studied

Critical Illness — all drugs for Critical Illness →

Sponsor

Menoufia University

Who can join

Adults 21 to 70, any sex, with Critical Illness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Upper gastrointestinal (GIT) bleeding is common in high risk critically ill patients. Hyperacidity has been identified as one of the main reasons for bleeding.1 2 Antacids with different treatment modalities have been studied to establish the best regimen for prophylaxis against bleeding.3 4 Proton pump inhibitors (PPI) are the most common drugs used in the medical field as antacids. The present study was carried out to investigate the beneficial effects of high dose omeprazole versus standard low dose as a prophylaxis against upper GIT bleeding in high risk critically ill patients.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Omeprazole

Trials testing the same drug.

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NCT07235748 — Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvas · Phase 1 · completed
NCT07149415 — A Study to Learn if Taking BIIB141 (Omaveloxolone) Affects How Omeprazole is Processed in the Body and About BIIB141's S · Phase 1 · completed
NCT06948006 — A Study to Investigate the Relative Bioavailability of 2 Different Formulations of AZD4144, the Effect of Food and Omepr · Phase 1 · completed

Other recruiting trials for Critical Illness

Currently open trials in the same condition.

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NCT07177183 — Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure · NA · recruiting
NCT07369258 — Clinical Application of Listening to Music to Prevent Delirium in the Intensive Care Unit · NA · recruiting

Other Menoufia University trials

Trials by the same sponsor.

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NCT07516236 — Dynamic SvO2 in Predicting Fluid Responsiveness in Septic Shock · not yet recruiting
NCT07485517 — Deep Versus Moderate Neuromuscular Blocking · NA · recruiting
NCT07506044 — Dexmedetomidine as an Adjuvant During Dural Puncture Epidural · NA · recruiting
NCT07322471 — Efficacy and Safety of Flexible Ureteroscopy Versus Percutaneous Nephrolithotomy in Management of Staghorn Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03388463 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Menoufia University
Last refreshed: 3 January 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03388463.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing