Last reviewed · How we verify
NCT03388242
Protein and microRNA Markers for Early Detection of Alzheimer's Disease
trial testing No intervention in Mild Cognitive Impairment. Withdrawn.
30 March 2020
Quick facts
| Lead sponsor | Sun Yat-sen University |
|---|---|
| Status | Withdrawn |
| Study type | OBSERVATIONAL |
| Start date | 7 December 2017 |
| Primary completion | 30 March 2020 |
| Estimated completion | 30 March 2020 |
| Sites | 2 locations across China |
Drugs / interventions tested
- No intervention
Conditions studied
- Mild Cognitive Impairment — all drugs for Mild Cognitive Impairment →
Sponsor
Sun Yat-sen University
Who can join
Adults 30 to 80, any sex, with Mild Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Blood will be harvested from three groups of people, normal control, patients with mild cognitive impairment (MCI) and patients with Alzheimer's disease (AD), 20 people per group. The blood samples will be used to determine the difference in the expression of microRNAs and proteins. Blood samples will be harvested again at 6-month interval from patients. The combination of the microRNAs and proteins that have different expression patterns between normal control and patients with MCI will be constructed in a kit to detect the difference. This kit will be used in another set of the three groups of people to determine its sensitivity and specificity in detecting patients with MCI.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
MicroRNAs as Potential Orchestrators of Alzheimer's Disease-Related Pathologies: Insights on Current Status and Future Possibilities.
Abuelezz NZ, Nasr FE, AbdulKader MA, Bassiouny AR, et al · · 2021 · cited 45× · PMID 34712129 · DOI 10.3389/fnagi.2021.743573 -
MicroRNA Networks in Cognition and Dementia.
Blount GS, Coursey L, Kocerha J. · · 2022 · cited 22× · PMID 35741010 · DOI 10.3390/cells11121882 -
Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases.
Ma YM, Zhao L. · · 2023 · cited 14× · PMID 38058356 · DOI 10.1155/2023/8537296
Verify or expand the search:
- PubMed search for NCT03388242
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Mild Cognitive Impairment
Currently open trials in the same condition.
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Other Sun Yat-sen University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03388242 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sun Yat-sen University
- Last refreshed: 23 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03388242.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing