Who is sponsoring NCT03386877?

NCT03386877 is sponsored by University of Turin, Italy.

What drugs are being tested in NCT03386877?

Interventions in NCT03386877: periodontal regeneration.

What condition does NCT03386877 study?

NCT03386877 studies Periodontal Diseases.

Is NCT03386877 still recruiting?

NCT03386877 is currently completed. Last updated 29 December 2017.

Last reviewed 2017-12-29 · How we verify

NCT03386877

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Periodontal Regeneration Using Dental Pulp Stem Cells (DPSCs)

Completed NA Last updated 29 December 2017

What this trial tests

NA trial testing periodontal regeneration in Periodontal Diseases in 29 participants. Completed in 28 April 2017.

Timeline

25 January 2016

Primary endpoint
28 April 2017

28 April 2017

Quick facts

Lead sponsor	University of Turin, Italy
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	29
Start date	25 January 2016
Primary completion	28 April 2017
Estimated completion	28 April 2017
Sites	2 locations across Italy

Drugs / interventions tested

periodontal regeneration

Conditions studied

Periodontal Diseases — all drugs for Periodontal Diseases →

Sponsor

University of Turin, Italy

Who can join

18 and older, any sex, with Periodontal Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to evaluate if dental pulp stem cells (DPSCs) delivered into intrabony defects in a collagen scaffold would enhance the clinical and radiographic parameters of periodontal regeneration.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

Stem cell-based bone and dental regeneration: a view of microenvironmental modulation.
Zheng C, Chen J, Liu S, Jin Y. · · 2019 · cited 162× · PMID 31423011 · DOI 10.1038/s41368-019-0060-3
Immunomodulatory properties of mesenchymal stem cells/dental stem cells and their therapeutic applications.
Li P, Ou Q, Shi S, Shao C. · · 2023 · cited 157× · PMID 36973490 · DOI 10.1038/s41423-023-00998-y
Promising advances in clinical trials of dental tissue-derived cell-based regenerative medicine.
Yamada Y, Nakamura-Yamada S, Konoki R, Baba S. · · 2020 · cited 48× · PMID 32398041 · DOI 10.1186/s13287-020-01683-x
Novel scaffold platforms for simultaneous induction osteogenesis and angiogenesis in bone tissue engineering: a cutting-edge approach.
Saberi A, Kouhjani M, Mohammadi M, Hosta-Rigau L. · · 2023 · cited 29× · PMID 37770928 · DOI 10.1186/s12951-023-02115-7
Immunomodulatory Properties of Stem Cells in Periodontitis: Current Status and Future Prospective.
Wang M, Xie J, Wang C, Zhong D, et al · · 2020 · cited 29× · PMID 32724318 · DOI 10.1155/2020/9836518
Clinical trials using dental stem cells: 2022 update.
Song WP, Jin LY, Zhu MD, Wang H, et al · · 2023 · cited 25× · PMID 37007456 · DOI 10.4252/wjsc.v15.i3.31
Adult Mesenchymal Stem Cells from Oral Cavity and Surrounding Areas: Types and Biomedical Applications.
Cabaña-Muñoz ME, Pelaz Fernández MJ, Parmigiani-Cabaña JM, Parmigiani-Izquierdo JM, et al · · 2023 · cited 22× · PMID 37631323 · DOI 10.3390/pharmaceutics15082109
Mechanisms underlying dental-derived stem cell-mediated neurorestoration in neurodegenerative disorders.
Raza SS, Wagner AP, Hussain YS, Khan MA. · · 2018 · cited 22× · PMID 30257724 · DOI 10.1186/s13287-018-1005-z

Verify or expand the search:

Other recruiting trials for Periodontal Diseases

Currently open trials in the same condition.

NCT07358104 — Efficacy of Camel Whey Protein and Camel Whey Protein Nanoparticles for Treating Intra-bony Periodontal Defects · NA · active not recruiting
NCT07312045 — HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical T · recruiting
NCT07384221 — Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients · recruiting
NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
NCT06848790 — Interdental Hygiene Methods in Young Adults · NA · recruiting

Other University of Turin, Italy trials

Trials by the same sponsor.

NCT06493188 — Low VS High-fidelity Interprofessional Simulation for ABG Skills Acquisition · NA · not yet recruiting
NCT07418489 — Biotics Intervention Oriented to Rescue From Environmental Pollution Inflammatory Responses · NA · enrolling by invitation
NCT07311291 — The Effect of Different Hemostatic Agents on Hemorrhage Control, Pain and Quality of Life After Endodontic Microsurgery. · NA · completed
NCT06904963 — Efficacy of Oral Hygiene Instructions Carried Out Using an Intra-oral Scanner · NA · completed
NCT07047261 — Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03386877 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Turin, Italy
Last refreshed: 29 December 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03386877.

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