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NCT03383315
Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
Phase 2 trial testing Tramadol in Trauma in 191 participants. Completed in 30 September 2017.
30 September 2017
Quick facts
| Lead sponsor | University of Malaya |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 191 |
| Start date | 1 July 2017 |
| Primary completion | 30 September 2017 |
| Estimated completion | 30 September 2017 |
| Sites | 1 location across Malaysia |
Drugs / interventions tested
- Tramadol (tramadol) — full drug profile →
- Metoclopramide (METOCLOPRAMIDE) — full drug profile →
- Placebo
Conditions studied
- Trauma — all drugs for Trauma →
- Opioid Analgesic Adverse Reaction — all drugs for Opioid Analgesic Adverse Reaction →
Sponsor
University of Malaya
Who can join
18 and older, any sex, with Trauma or Opioid Analgesic Adverse Reaction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Tramadol is widely used as analgesic in trauma patients. However, it causes side effects, most notably nausea and vomiting. This study aim to determine the role of prophylactic metoclopramide in preventing tramadol induced nausea and vomiting.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03383315
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Trauma
Currently open trials in the same condition.
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Other University of Malaya trials
Trials by the same sponsor.
- NCT07398066 — DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial) · NA · not yet recruiting
- NCT07522463 — Enhancing Attention and Processing Speed Through Home-based Music Rehabilitation Program After Stroke in Malaysia · NA · not yet recruiting
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- NCT07452705 — Small Study Comparing Two Pain Medicines in Teenagers for Pain Control After Scoliosis Corrective Surgery. · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03383315 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Malaya
- Last refreshed: 26 December 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03383315.
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