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NCT02880163: REVIVE

REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam

Recruiting now NA Last updated 10 November 2025
What this trial tests

NA trial testing ResQFoam in Hemorrhagic Shock in 40 participants. Currently enrolling.

Timeline
7 August 2025
Primary endpoint
31 October 2026
31 December 2026

Quick facts

Lead sponsorArsenal Medical, Inc.
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment40
Start date7 August 2025
Primary completion31 October 2026
Estimated completion31 December 2026
Sites2 locations across United States

Drugs / interventions tested

Conditions studied

Sponsor

Arsenal Medical, Inc.

Who can join

15 and older, any sex, with Hemorrhagic Shock or Trauma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to demonstrate safety, effectiveness and benefit-risk profile of ResQFoam for the inhospital treatment of exsanguinating, intraabdominal haemorrhage due to trauma in patients where emergent laparotomy is required.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Traumatic hemorrhage and chain of survival.
    Latif RK, Clifford SP, Baker JA, Lenhardt R, et al · · 2023 · cited 74× · PMID 37226264 · DOI 10.1186/s13049-023-01088-8
  2. Hemostatic agents for prehospital hemorrhage control: a narrative review.
    Peng HT. · · 2020 · cited 70× · PMID 32209132 · DOI 10.1186/s40779-020-00241-z
  3. Development of Optimized Tissue-Factor-Targeted Peptide Amphiphile Nanofibers to Slow Noncompressible Torso Hemorrhage.
    Klein MK, Kassam HA, Lee RH, Bergmeier W, et al · · 2020 · cited 30× · PMID 32469498 · DOI 10.1021/acsnano.9b09243
  4. Optimizing transfusion strategies in damage control resuscitation: current insights.
    Pohlman TH, Fecher AM, Arreola-Garcia C. · · 2018 · cited 5× · PMID 30154676 · DOI 10.2147/jbm.s165394

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Other recruiting trials for Hemorrhagic Shock

Currently open trials in the same condition.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02880163.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing