Last reviewed · How we verify
NCT03326908: ODIGIT
Description of the Interdigitation Retinal Area by SD-OCT: An Exploratory Study
NA trial testing Spectral Domain Optical Coherence Tomography in Tomography, Optical Coherence in 20 participants. Completed in 24 January 2018.
10 January 2018
Quick facts
| Lead sponsor | Fondation Ophtalmologique Adolphe de Rothschild |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 20 |
| Start date | 12 October 2017 |
| Primary completion | 10 January 2018 |
| Estimated completion | 24 January 2018 |
| Sites | 1 location across France |
Drugs / interventions tested
- Spectral Domain Optical Coherence Tomography
Conditions studied
- Tomography, Optical Coherence — all drugs for Tomography, Optical Coherence →
- Retina — all drugs for Retina →
Sponsor
Fondation Ophtalmologique Adolphe de Rothschild — full company profile →
Who can join
18 and older, any sex, with Tomography, Optical Coherence or Retina. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Improvement of retinal medical imaging opens new perspectives for exploring the retinal structures. Optical coherence spectral domain (SD-OCT), which has been widely used in the last ten years, is certainly the most advanced device. In the analysis of patients without retinal disease using SD-OCT, granulations in the interdigitation area were observed. These granulations have never been described with this device. They could correspond either to the degradation products of the external segments of the photoreceptors or to melanosomes. A descriptive study of these granulations at different examination times and in different lighting situations would allow us to obtain essential information for a better understanding of this area. Based on the results, larger studies could explore this area more finely in retinal pathologies involving dysfunctions of photoreceptors or of the pigmentary epithelium.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Light-induced modifications of the outer retinal hyperreflective layers on spectral-domain optical coherence tomography in humans: an experimental study.
Mathis T, Vasseur V, Zuber K, Arej N, et al · · 2021 · cited 3× · PMID 33393736 · DOI 10.1111/aos.14723
Verify or expand the search:
- PubMed search for NCT03326908
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03326908 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fondation Ophtalmologique Adolphe de Rothschild
- Last refreshed: 6 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03326908.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing