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NCT05728216: NEPHROCT
Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Injury or Chronic Kidney Disease in Routine Practices (NEPHROCT)
trial testing Dynamic full-field optical coherence tomography analysis of kidney biopsy in Acute Kidney Injury in 50 participants. Currently enrolling.
31 October 2028
Quick facts
| Lead sponsor | Centre Hospitalier William Morey - Chalon sur Saône |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 November 2022 |
| Primary completion | 31 October 2028 |
| Estimated completion | 30 November 2028 |
| Sites | 1 location across France |
Drugs / interventions tested
- Dynamic full-field optical coherence tomography analysis of kidney biopsy
Conditions studied
- Acute Kidney Injury — all drugs for Acute Kidney Injury →
- Chronic Kidney Diseases — all drugs for Chronic Kidney Diseases →
- Tomography, Optical Coherence — all drugs for Tomography, Optical Coherence →
Sponsor
Centre Hospitalier William Morey - Chalon sur Saône
Who can join
18 and older, any sex, with Acute Kidney Injury or Chronic Kidney Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Kidney biopsy play a key role for the investigation of either acute kidney injury or chronic kidney disease. Despite possible complications due to the invasive nature of the biopsy, such procedure is still essential in a number of clinical situations to improve the diagnosis specificity of kidney disease, better inform about its prognosis and guide the management of a future treatment. Pursuing the idea to improve both performance and rapidity associated with the histopathological analysis of kidney biopsy, with a possible recourse to artificial intelligence-based renal pathology, the present study intends to assess the impact of direct histopathological examination of kidney biopsy with dynamic full-field optical coherence tomography in routine practices for the diagnosis of either acute kidney injury or chronic kidney disease.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Rapid On-Site Histopathological Analysis of Kidney Biopsy With Dynamic Full-Field Optical Coherence Tomography.
Zuccarelli L, Bernard Q, Tarris G, Martin L, et al · · 2025 · cited 2× · PMID 40485696 · DOI 10.1016/j.ekir.2025.01.047
Verify or expand the search:
- PubMed search for NCT05728216
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Acute Kidney Injury
Currently open trials in the same condition.
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Other Centre Hospitalier William Morey - Chalon sur Saône trials
Trials by the same sponsor.
- NCT06611800 — Personalized Advance Prescriptions in Palliative Care at HOME: Interests and Difficulties of Its Implementation · completed
- NCT06216080 — Dynamic Full-Field Optical Coherence Tomography for Structural and Microbiological Characterization of Central Venous Ca · completed
- NCT05663333 — Histopathological Analysis of Temporal Artery Biopsy Following Dynamic Full-field Optical Coherence Tomography, a Compar · completed
- NCT05608902 — Structural Description of Skin Biopsies With Dynamic Full-field Optical Coherence Tomography on Suspected Basal Cell Car · completed
- NCT05635136 — Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conve · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05728216 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier William Morey - Chalon sur Saône
- Last refreshed: 18 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05728216.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing