NCT03325608: POISED

Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients

Completed NA Results posted Last updated 16 October 2024

What this trial tests

NA trial testing POISED Care in Dementia in 889 participants. Completed in 2 November 2021.

Timeline

7 March 2018

Primary endpoint
2 November 2021

2 November 2021

Quick facts

Lead sponsor	NYU Langone Health
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	889
Start date	7 March 2018
Primary completion	2 November 2021
Estimated completion	2 November 2021
Sites	1 location across United States

Drugs / interventions tested

• POISED Care

Conditions studied

• Dementia — all drugs for Dementia →

Sponsor

NYU Langone Health — full company profile →

Who can join

75 and older, any sex, with Dementia. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Percentage of Participants With an Emergency Department (ED) Visit Within 6 Months After Enrollment Primary · Up to Month 6

Percentage of participants who visit the ED within 6 months of being enrolled.

Group	Value	95% CI
POISED Care Intervention - Patients	41.60	36.1 – 47.3
Usual Care - Patients	39.40	34.0 – 45.1

Sponsor's own description

Dementia is a common problem for older patients presenting to emergency departments and for the family caregivers who often lack support, understanding, and skills to manage the problems related to the need for emergency department visits. The purpose of Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients (POISED-CPCIP, here on referred to as POISED) randomized controlled trial is to use previously established quality improvement methods of root cause analysis to uncover reasons for emergency department use and to focus on caregiver activation within a program of dementia care management.

The goals of this study are to reduce recurrent emergency department visits and improve caregiver symptoms of depression, anxiety and need for social support.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients: Protocol for a Multisite Randomized Controlled Trial.
   Chodosh J, Connor K, Fowler N, Gao S, et al · · 2022 · cited 2× · PMID 36264626 · DOI 10.2196/36607
2. Program of intensive support in emergency departments for care partners of cognitively impaired patients: A randomized controlled trial.
   Chodosh J, Fowler NR, Perkins AJ, Connor KI, et al · · 2025 · cited 1× · PMID 40399761 · DOI 10.1002/alz.70306