NCT03325114 is a Phase 2 clinical trial of Chlorthalidone in Type 1 Diabetes Mellitus, sponsored by University of Rochester.

Who is sponsoring NCT03325114?

NCT03325114 is sponsored by University of Rochester.

What drugs are being tested in NCT03325114?

Interventions in NCT03325114: Chlorthalidone.

What condition does NCT03325114 study?

NCT03325114 studies Type 1 Diabetes Mellitus, Hypercalciuria.

Is NCT03325114 still recruiting?

NCT03325114 is currently terminated. Last updated 5 January 2021.

Are results published for NCT03325114?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2021-01-05 · How we verify

NCT03325114

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Safety and Efficacy of Chlorthalidone in Type 1 Diabetes

Terminated Phase 2 Results posted Last updated 5 January 2021

What this trial tests

Phase 2 trial testing Chlorthalidone in Type 1 Diabetes Mellitus in 1 participant. Terminated before completion.

Timeline

28 June 2019

Primary endpoint
1 June 2020

1 June 2020

Quick facts

Lead sponsor	University of Rochester
Phase	Phase 2
Status	Terminated
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	1
Start date	28 June 2019
Primary completion	1 June 2020
Estimated completion	1 June 2020
Sites	1 location across United States

Drugs / interventions tested

Chlorthalidone — full drug profile →

Conditions studied

Type 1 Diabetes Mellitus — all drugs for Type 1 Diabetes Mellitus →
Hypercalciuria — all drugs for Hypercalciuria →

Sponsor

University of Rochester

Who can join

Adults 12 to 21, any sex, with Type 1 Diabetes Mellitus or Hypercalciuria. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This open-label study will determine if chlorthalidone is safe and effective for the use of reducing urinary calcium excretion over 4 weeks in subjects with type 1 diabetes

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Chlorthalidone

Trials testing the same drug.

NCT07225764 — CaOx Stone Prevention · Phase 4 · recruiting
NCT05593055 — Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension · Phase 4 · recruiting
NCT05915286 — Diuretic Use in Hemodialysis Patients With Residual Renal Function · Phase 4 · suspended
NCT05275907 — Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN) · Phase 4 · withdrawn
NCT05222191 — Spironolactone in CKD Enabled by Chlorthalidone: PILOT · Phase 2 · unknown

Other recruiting trials for Type 1 Diabetes Mellitus

Currently open trials in the same condition.

NCT07142252 — Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus · Phase 2 · recruiting
NCT07296276 — Accuracy and Precision of the Continuous Glucose Monitoring System 'CareSens Air 3' in Adult Patients With T1DM · NA · recruiting
NCT07409701 — Gamification Intervertion in Children With Type 1 Diabetes · NA · recruiting
NCT07356089 — Twiist Postmarket Surveillance Study for Type 1 Diabetes · recruiting
NCT07434154 — Evaluation of Oxidative Stress: Comparison Between Type 1 Diabetes Mellitus and Latent Autoimmune Diabetes in Adults · recruiting

Other University of Rochester trials

Trials by the same sponsor.

NCT07075965 — Calcium Channel Blocker in Myotonic Dystrophy Type 1 · Phase 1 · not yet recruiting
NCT07423104 — A Study of Cladribine, Low Dose Cytarabine, and Venetoclax in Treatment of Relapsed/Refractory or Secondary Acute Myeloi · Phase 2 · not yet recruiting
NCT05744869 — SBAT for Health Equity · NA · not yet recruiting
NCT06052956 — Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses · Phase 2 · not yet recruiting
NCT07032636 — Reducing Crises and Suicide Within the Idaho Army National Guard · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03325114 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Rochester
Last refreshed: 5 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03325114.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing