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NCT03310203

The Relation Between Adiposity, Inflammation, Glycaemia and Iron Absorption

Completed NA Last updated 11 January 2019
What this trial tests

NA trial testing Iron in Iron Absorption in 126 participants. Completed in 5 December 2018.

Timeline
27 September 2017
Primary endpoint
5 December 2018
5 December 2018

Quick facts

Lead sponsorAmerican University of Beirut Medical Center
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposebasic science
Enrollment126
Start date27 September 2017
Primary completion5 December 2018
Estimated completion5 December 2018
Sites1 location across Lebanon

Drugs / interventions tested

Conditions studied

Sponsor

American University of Beirut Medical Center

Who can join

Adults 20 to 50, female only, with Iron Absorption. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A total of 126 premenopausal women (42 lean, 42 obese with central obesity, 42 obese with peripheral obesity) will be recruited. Anthropometric measurements and body composition using DEXA will be collected. Overnight fasted subjects will be asked to give baseline blood samples before consuming a meal containing 6 mg 57Fe in the form of FeSO4. Subjects will return after 14 days and a blood sample will be collected for measurement of isotopic enrichment into red blood cells, serving as well as a baseline for the OGTT. Subjects will then be asked to ingest a solution of glucose (50g) containing 100 mg of iron in the form of sodium ferrous citrate (SFC), after which blood samples will be collected 2 hours post iron and glucose load. All three blood samples collected at baseline, 2 weeks post labeled iron load, and 2 hours post glucose/iron load will be analyzed for their levels of iron, glycaemia and inflammatory parameters.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Iron

Trials testing the same drug.

Other recruiting trials for Iron Absorption

Currently open trials in the same condition.

Other American University of Beirut Medical Center trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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