NCT03309072

Investigating Accelerated Learning and Memory in Healthy Subjects Using a Face Name Memory Task

Completed NA Results posted Last updated 3 February 2022

What this trial tests

NA trial testing tDCS in Healthy Adults in 30 participants. Completed in 25 January 2022.

Timeline

27 September 2017

Primary endpoint
25 January 2022

25 January 2022

Quick facts

Lead sponsor	The University of Texas at Dallas
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	basic science
Enrollment	30
Start date	27 September 2017
Primary completion	25 January 2022
Estimated completion	25 January 2022
Sites	1 location across United States

Drugs / interventions tested

• tDCS — full drug profile →
• sham tDCS

Conditions studied

• Healthy Adults — all drugs for Healthy Adults →

Sponsor

The University of Texas at Dallas

Who can join

Adults 18 to 35, any sex, with Healthy Adults. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Associative Memory Assessed by a Face Name Associate Memory Experiment Primary · Associate Memory is assessed after a 10 minutes break following the study phase

All participants performed a face memory task .The face stimuli consisted of 120 grayscale pictures of human faces. Only faces with a neutral expression facing forward were selected. Half of the faces were male, and the other half were female. The face-name association memory task was divided into (1) an encoding phase, (2) a consolidation phase, and (3) a retrieval phase. During the encoding phase, participants studied 60 successively presented face-name pairs and were instructed to assess their gender to keep them focused to the task. The encoding phase was followed by a consolidation phase

Group	Value	95% CI
Active tDCS	44.22	± 11.54
Sham tDCS	35.44	± 12.04

Sponsor's own description

The purpose of this study is to investigate whether we can accelerate learning and improve associative memory performance in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. The peripheral effect of direct current stimulation on brain circuits involving memory.
   Vanneste S, Mohan A, Yoo HB, Huang Y, et al · · 2020 · cited 47× · PMID 33148657 · DOI 10.1126/sciadv.aax9538