Last reviewed · How we verify
NCT03305900
Determinants of Formate Concentrations
trial testing No Intervention in Healthy in 1,701 participants. Completed in 26 November 2013.
26 November 2013
Quick facts
| Lead sponsor | Memorial University of Newfoundland |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,701 |
| Start date | 1 December 2012 |
| Primary completion | 26 November 2013 |
| Estimated completion | 26 November 2013 |
Drugs / interventions tested
- No Intervention
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
Memorial University of Newfoundland
Who can join
Adults 18 to 28, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Formate is an important metabolite, serving as a donor of one-carbon groups to the intracellular tetrahydrofolate pool. However, little is known of its circulating concentrations or of their determinants. This study seeks to define formate levels and their determinants in a young, healthy population. Serum formate will be measured in 1701 subjects from the Trinity Student Study. The subjects, males and females, aged 18 to 28 years, were enrolled at Trinity College, Dublin. Formate levels will be compared with other one-carbon metabolites, vitamin status, potential formate precursors, genetic polymorphisms, and lifestyle factors.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Lifestyle, metabolite, and genetic determinants of formate concentrations in a cross-sectional study in young, healthy adults.
Brosnan JT, Mills JL, Ueland PM, Shane B, et al · · 2018 · cited 8× · PMID 29566195 · DOI 10.1093/ajcn/nqx065
Verify or expand the search:
- PubMed search for NCT03305900
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03305900 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Memorial University of Newfoundland
- Last refreshed: 10 October 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03305900.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing