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NCT06714331
Caffeine and Sodium Bicarbonate Supplementation Effects on Resistance Training Performance
EARLY_PHASE1 trial testing Supplements in Nutritional Supplementation in 12 participants. Completed in 5 May 2025.
5 April 2025
Quick facts
| Lead sponsor | Memorial University of Newfoundland |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 12 |
| Start date | 1 August 2024 |
| Primary completion | 5 April 2025 |
| Estimated completion | 5 May 2025 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Supplements
Conditions studied
- Nutritional Supplementation — all drugs for Nutritional Supplementation →
- Resistance Training — all drugs for Resistance Training →
Sponsor
Memorial University of Newfoundland
Who can join
Adults 18 to 40, any sex, with Nutritional Supplementation or Resistance Training. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research aims to explore the effects of two supplements, caffeine and sodium bicarbonate, on acute (short-term) resistance training performance. The present study aims to assess the effects of caffeine and sodium bicarbonate supplementation on the number of repetitions, muscle activation, speed of movement, and fatigue during resistance training.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
No Ergogenic Effect of Caffeine or Sodium Bicarbonate on Resistance Exercise Performance: A Double-Blind Crossover Study with Sex-Based Analysis.
Williams MLA, Barrett CME, Lawson E, Major CP, et al · · 2025 · PMID 41441411 · DOI 10.3390/sports13120427
Verify or expand the search:
- PubMed search for NCT06714331
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06714331 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Memorial University of Newfoundland
- Last refreshed: 17 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06714331.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing