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NCT03297749
Genetic Variants and Oxidative Stress as Links Between Periodontitis and Metabolic Syndrome
trial testing Observational study (no intervention) in Periodontitis, Adult in 102 participants. Status unknown.
30 September 2017
Quick facts
| Lead sponsor | University College, London |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 102 |
| Start date | 1 July 2015 |
| Primary completion | 30 September 2017 |
| Estimated completion | 31 December 2020 |
| Sites | 2 locations across Italy, United Kingdom |
Drugs / interventions tested
- Observational study (no intervention)
Conditions studied
- Periodontitis, Adult — all drugs for Periodontitis, Adult →
- Metabolic Syndrome — all drugs for Metabolic Syndrome →
Sponsor
University College, London
Who can join
Adults 18 to 75, any sex, with Periodontitis, Adult or Metabolic Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to investigate the systemic impact of periodontitis in patients with Metabolic Syndrome, by assessing measures of sub-clinical atherosclerosis and cardiovascular risk, microbial factors and host genetic variants, and to study the possible effect of mediators of inflammation and oxidative stress as links between the two conditions.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Left ventricular geometry and periodontitis in patients with the metabolic syndrome.
Nibali L, Donos N, Terranova V, Di Pino A, et al · · 2019 · cited 18× · PMID 30350134 · DOI 10.1007/s00784-018-2667-8 -
Associations between Host Genetic Variants and Subgingival Microbiota in Patients with the Metabolic Syndrome.
Nibali L, Stephen AS, Allaker RP, Di Pino A, et al · · 2023 · cited 4× · PMID 38068972 · DOI 10.3390/ijms242316649
Verify or expand the search:
- PubMed search for NCT03297749
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03297749 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University College, London
- Last refreshed: 26 October 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03297749.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing