Adults 6 to 14, any sex, with Cystic Fibrosis. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Exercise TolerancePrimary· Before treatment
Modified Shuttle Test (MST) is used to measure the exercise tolerance. The patient is asked to walk until feeling tired between two fixed objects with a 10-meter interval, starting at normal walking speed and increasing the speed at the beginning of each minute. Maximum distance (meters) is measured for the test.
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
817
± 234.62
Pulmonary Rehabilitation Group
792.22
± 327.21
Exercise TolerancePrimary· 6 weeks
Modified Shuttle Test (MST) is used to measure the exercise tolerance. The patient is asked to walk until feeling tired between two fixed objects with a 10-meter interval, starting at normal walking speed and increasing the speed at the beginning of each minute. Maximum distance (meters) is measured for the test.
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
980
± 277.24
Pulmonary Rehabilitation Group
1058.77
± 594.67
Exercise TolerancePrimary· 3 months
Modified Shuttle Test (MST) is used to measure the exercise tolerance. The patient is asked to walk until feeling tired between two fixed objects with a 10-meter interval, starting at normal walking speed and increasing the speed at the beginning of each minute. Maximum distance (meters) is measured for the test.
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
1104
± 306.73
Pulmonary Rehabilitation Group
1036.66
± 457.16
Exercise TolerancePrimary· 6 months
Modified Shuttle Test (MST) is used to measure the exercise tolerance. The patient is asked to walk until feeling tired between two fixed objects with a 10-meter interval, starting at normal walking speed and increasing the speed at the beginning of each minute. Maximum distance (meters) is measured for the test.
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
1251
± 324.15
Pulmonary Rehabilitation Group
1161.11
± 594.06
Quality of LifeSecondary· Before treatment
The Cystic Fibrosis Questionnaire-Revised (CFQR) is used to measure the quality of life. This scale is found to be valid and reliable in Turkish. The child version of this test consists 35 questions about physical function, emotional function, social function, body appearance, eating disorders, treatment difficulties, respiratory and digestive symptoms. The total score is calculated between 0-100 and higher scores define the better condition.
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
86.4
± 5.75
Pulmonary Rehabilitation Group
92.77
± 9.94
Quality of LifeSecondary· 6 weeks
The Cystic Fibrosis Questionnaire-Revised (CFQR) is used to measure the quality of life. This scale is found to be valid and reliable in Turkish. The child version of this test consists 35 questions about physical function, emotional function, social function, body appearance, eating disorders, treatment difficulties, respiratory and digestive symptoms. The total score is calculated between 0-100 and higher scores define the better condition.
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
88.9
± 7.04
Pulmonary Rehabilitation Group
90.88
± 13.37
Quality of LifeSecondary· 3 months
The Cystic Fibrosis Questionnaire-Revised (CFQR) is used to measure the quality of life. This scale is found to be valid and reliable in Turkish. The child version of this test consists 35 questions about physical function, emotional function, social function, body appearance, eating disorders, treatment difficulties, respiratory and digestive symptoms. The total score is calculated between 0-100 and higher scores define the better condition.
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
87.2
± 5.57
Pulmonary Rehabilitation Group
93.33
± 11.35
Quality of LifeSecondary· 6 months
The Cystic Fibrosis Questionnaire-Revised (CFQR) is used to measure the quality of life. This scale is found to be valid and reliable in Turkish. The child version of this test consists 35 questions about physical function, emotional function, social function, body appearance, eating disorders, treatment difficulties, respiratory and digestive symptoms. The total score is calculated between 0-100 and higher scores define the better condition.
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
89.7
± 7.84
Pulmonary Rehabilitation Group
95.55
± 12.64
Postural StabilitySecondary· Before treatment
The Balance Master Device- Limits of Stability Test (LOS) is used for to measure the postural stability of children. The LOS consists a 18x60 inch of a pressure platform which connected to a computer system. The patient is asked to stand on the platform barefoot and watch the image which can be moved by trunk movement on the computer the monitor. It is required to move the image towards to target points on the monitor with commands. Reaction time, movement velocity, endpoint excursion, maximum excursion and direction control parameters are calculated during these trunk movements. Reaction time
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
1.29
± 0.85
Pulmonary Rehabilitation Group
1.03
± 0.53
Postural StabilitySecondary· 6 weeks
The Balance Master Device- Limits of Stability Test (LOS) is used for to measure the postural stability of children. The LOS consists a 18x60 inch of a pressure platform which connected to a computer system. The patient is asked to stand on the platform barefoot and watch the image which can be moved by trunk movement on the computer the monitor. It is required to move the image towards to target points on the monitor with commands. Reaction time, movement velocity, endpoint excursion, maximum excursion and direction control parameters are calculated during these trunk movements. Reaction time
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
0.91
± 0.66
Pulmonary Rehabilitation Group
0.83
± 0.65
Postural StabilitySecondary· 3 months
The Balance Master Device- Limits of Stability Test (LOS) is used for to measure the postural stability of children. The LOS consists a 18x60 inch of a pressure platform which connected to a computer system. The patient is asked to stand on the platform barefoot and watch the image which can be moved by trunk movement on the computer the monitor. It is required to move the image towards to target points on the monitor with commands. Reaction time, movement velocity, endpoint excursion, maximum excursion and direction control parameters are calculated during these trunk movements. Reaction time
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
0.88
± 0.72
Pulmonary Rehabilitation Group
0.65
± 0.52
Postural StabilitySecondary· 6 months
The Balance Master Device- Limits of Stability Test (LOS) is used for to measure the postural stability of children. The LOS consists a 18x60 inch of a pressure platform which connected to a computer system. The patient is asked to stand on the platform barefoot and watch the image which can be moved by trunk movement on the computer the monitor. It is required to move the image towards to target points on the monitor with commands. Reaction time, movement velocity, endpoint excursion, maximum excursion and direction control parameters are calculated during these trunk movements. Reaction time
Group
Value
95% CI
Pulmonary Rehabilitation+Exercise Group
1.15
± 0.69
Pulmonary Rehabilitation Group
0.92
± 0.46
Sponsor's own description
The aim of this study is to investigate the effects of postural exercise program added to pulmonary rehabilitation program on quality of life, exercise tolerance and postural stability in children with Cystic Fibrosis.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
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NCT06810167 — Assessing Tenapanor as a Treatment of CF-related Constipation.
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NCT06962852 — A Long-term Study to Monitor the Health Status of People With Cystic Fibrosis Who Took Part in a Previous Study With BI
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Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Marmara University
Last refreshed: 26 October 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03295201.