NCT03276390: HKTP

A Culturally Targeted Transplant Program

Completed NA Last updated 3 October 2022

What this trial tests

NA trial testing Hispanic Kidney Transplant Program (HKTP) in ESRD in 11,836 participants. Completed in 28 February 2021.

Timeline

18 January 2017

Primary endpoint
28 February 2021

28 February 2021

Quick facts

Lead sponsor	Northwestern University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	health services research
Enrollment	11,836
Start date	18 January 2017
Primary completion	28 February 2021
Estimated completion	28 February 2021
Sites	4 locations across United States

Drugs / interventions tested

• Hispanic Kidney Transplant Program (HKTP)

Conditions studied

• ESRD — all drugs for ESRD →

Sponsor

Northwestern University

Who can join

Adults 18 to 100, any sex, with ESRD. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hispanic/Latino patients with end-stage renal disease are disproportionately less likely to get a kidney transplant, and specifically, a living donor kidney transplant (LDKT), compared to non-Hispanic whites. Accordingly, without LDKTs, Hispanics experience longer transplant waiting times, shorter patient and graft survival, and worse quality of life. Cultural beliefs and linguistic barriers contribute to the disparity in LDKTs. The objective of the proposed study is to implement and evaluate Northwestern Medicine's® Hispanic Kidney Transplant Program, a culturally-competent transplant center-based intervention, at two transplant centers serving large Hispanic populations. The proposed study will provide valuable knowledge about the potential to rapidly disseminate the HKTP as a novel approach to increase Hispanic LDKTs nationally.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

1. Effectiveness of a culturally competent care intervention in reducing disparities in Hispanic live donor kidney transplantation: A hybrid trial.
   Gordon EJ, Uriarte JJ, Lee J, Kang R, et al · · 2022 · cited 33× · PMID 34559944 · DOI 10.1111/ajt.16857
2. A complex culturally targeted intervention to reduce Hispanic disparities in living kidney donor transplantation: an effectiveness-implementation hybrid study protocol.
   Gordon EJ, Lee J, Kang RH, Caicedo JC, et al · · 2018 · cited 33× · PMID 29769080 · DOI 10.1186/s12913-018-3151-5
3. Implementing culturally competent transplant care and implications for reducing health disparities: A prospective qualitative study.
   Gordon EJ, Romo E, Amórtegui D, Rodas A, et al · · 2020 · cited 23× · PMID 33037746 · DOI 10.1111/hex.13124
4. Disparities Persist Among Hispanic Patients: Completing Evaluation, Waitlisting, and Receiving a Kidney Transplant.
   Gordon EJ, Lee J, Kang R, Uriarte J, et al · · 2024 · cited 11× · PMID 38414978 · DOI 10.1097/txd.0000000000001595
5. Financial Feasibility Analysis of a Culturally and Linguistically Competent Hispanic Kidney Transplant Program.
   Wang A, Caicedo JC, McNatt G, Abecassis M, et al · · 2021 · cited 10× · PMID 32282660 · DOI 10.1097/tp.0000000000003269
6. Patients' perceptions of a culturally targeted Hispanic Kidney Transplant Program: A mixed methods study.
   Alhalel N, Francone NO, Salazar AM, Primeaux S, et al · · 2019 · cited 8× · PMID 31034642 · DOI 10.1111/ctr.13577
7. Financial Impact of a Culturally Sensitive Hispanic Kidney Transplant Program on Increasing Living Donation.
   Wang A, Caicedo JC, Mathur AK, Ruiz RM, et al · · 2023 · cited 7× · PMID 36346212 · DOI 10.1097/tp.0000000000004382
8. Implementation and modification of an organizational-level intervention: a prospective analysis.
   Gordon EJ, Uriarte JJ, Anderson N, Romo E, et al · · 2022 · cited 6× · PMID 35659156 · DOI 10.1186/s43058-022-00296-0