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NCT05339139: SARCA
SAfety of Regional Citrate Anticoagulation (SARCA Study)
Phase 3 trial testing Dialysis in Acute Kidney Injury in 50 participants. Currently enrolling.
30 April 2025
Quick facts
| Lead sponsor | Fresenius Medical Care North America |
|---|---|
| Phase | Phase 3 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 17 October 2023 |
| Primary completion | 30 April 2025 |
| Estimated completion | 31 July 2025 |
| Sites | 10 locations across United States |
Drugs / interventions tested
- Dialysis
Conditions studied
- Acute Kidney Injury — all drugs for Acute Kidney Injury →
- ESRD — all drugs for ESRD →
Sponsor
Fresenius Medical Care North America — full company profile →
Who can join
18 and older, any sex, with Acute Kidney Injury or ESRD. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is an Open-label, Prospective, Multicenter Study to Assess the SAfety of Regional Citrate Anticoagulation Delivered by the multiFiltratePRO system in Adult Patients Requiring Continuous Renal Replacement Therapy (SARCA Study).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05339139
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dialysis
Trials testing the same drug.
- NCT07051447 — The Reducing Adverse Outcomes in Dialysis by Adjusting the pRescription for Dialysate Potassium Trial · NA · not yet recruiting
- NCT06019871 — The Danish Symptomburden Study Among Patients With Advanced Kidney Disease · unknown
- NCT04218370 — Liberation From Acute Dialysis · NA · completed
Other recruiting trials for Acute Kidney Injury
Currently open trials in the same condition.
- NCT07273838 — Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome · Phase 2 · recruiting
- NCT07262320 — Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America · recruiting
- NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
- NCT07215702 — A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kid · Phase 2 · recruiting
- NCT06654193 — Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury · Phase 1, PHASE2 · recruiting
Other Fresenius Medical Care North America trials
Trials by the same sponsor.
- NCT04511338 — Feasibility Study for Heparin-free Hemodialysis With the Dialyzer With Endexo™ · NA · completed
- NCT04573595 — Fresenius Noninvasive Blood Pressure Validation · NA · completed
- NCT03536663 — Clinical Study to Assess the Performance of the Dialyzer With Endexo™ · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05339139 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fresenius Medical Care North America
- Last refreshed: 24 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05339139.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing