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NCT03274037: g-BrainMRE
Evaluation of Cerebral Elastography by Magnetic Resonance: Comparison of Healthy Subjects and Patients With Glial Tumor
NA trial testing Device for mechanical excitation by pressure waves in Elasticity Imaging Techniques in 48 participants. Status unknown.
7 July 2020
Quick facts
| Lead sponsor | Assistance Publique - Hôpitaux de Paris |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 48 |
| Start date | 7 July 2017 |
| Primary completion | 7 July 2020 |
| Estimated completion | 7 July 2020 |
| Sites | 1 location across France |
Drugs / interventions tested
- Device for mechanical excitation by pressure waves
Conditions studied
- Elasticity Imaging Techniques — all drugs for Elasticity Imaging Techniques →
Sponsor
Assistance Publique - Hôpitaux de Paris — full company profile →
Who can join
Adults 18 to 65, any sex, with Elasticity Imaging Techniques. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
MRI elastography detects the movement of tissues in the human body and monitors their response to mechanical stress in order to reveal their mechanical properties, like palpation. These depend on the structure of the tissues, their biological conditions and possible conditions. This non-invasive technique allows exploration of deep organs such as the brain that the doctor's hand can not reach. MRI elastography may prove to be an essential tool for study, diagnosis, staging and therapeutic monitoring of brain diseases. Neurodegenerative diseases (Alzheimer's, Parkinson's, Creutzfeldt-Jakobes) and cancers largely modify the mechanical properties of the affected tissues. For a first evaluation of the technique, we are interested in glial tumors representing half of the intracranial tumors in adults (incidence: 5 cases per 100 000 inhabitants), the second cancer in children and the third cause of death in l Young adult.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Mechanotransduction: Exploring New Therapeutic Avenues in Central Nervous System Pathology.
Rocha DN, Carvalho ED, Relvas JB, Oliveira MJ, et al · · 2022 · cited 21× · PMID 35573316 · DOI 10.3389/fnins.2022.861613
Verify or expand the search:
- PubMed search for NCT03274037
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Elasticity Imaging Techniques
Currently open trials in the same condition.
- NCT04781894 — Application of Transthoracic Shear-wave Ultrasound Elastography in Pleural Lesions · recruiting
- NCT03376425 — Transthoracic Shear-wave Ultrasound Elastography · recruiting
Other Assistance Publique - Hôpitaux de Paris trials
Trials by the same sponsor.
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- NCT07499492 — Red Blood Cell Transfusion to Optimize Extubation · NA · not yet recruiting
- NCT07379918 — Real-life Evaluation of Endopredict® in Early HR+/HER2- Breast Cancer · recruiting
- NCT07473869 — Smartphone Application for Automated Measurement of Capillary Refill Time (CRT) · not yet recruiting
- NCT07505394 — Efficacy of a Prediction Model-based Algorithm to PREVENT Drug-induced Impulse Control Disorders in Parkinson's Disease · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03274037 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assistance Publique - Hôpitaux de Paris
- Last refreshed: 8 September 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03274037.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing