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NCT03261674

Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain Injury

Completed NA Results posted Last updated 31 October 2024
What this trial tests

NA trial testing CBT-I in Insomnia in 110 participants. Completed in 25 April 2024.

Timeline
28 June 2018
Primary endpoint
30 September 2023
25 April 2024

Quick facts

Lead sponsorVA Office of Research and Development
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposetreatment
Enrollment110
Start date28 June 2018
Primary completion30 September 2023
Estimated completion25 April 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

VA Office of Research and Development — full company profile →

Who can join

Eligibility, any sex, with Insomnia or Traumatic Brain Injury. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Insomnia Severity Index (ISI) Primary · Change from baseline at week 8 after treatment

The primary outcome measure is the Veteran's subjective experience of severity of insomnia measured with the Insomnia Severity Index (ISI). The ISI has been shown to be a reliable subjective measure of insomnia severity as well as a sensitive measure of symptom change. This 7-item instrument results in total scores ranging from 0 to 28, with higher scores indicating more severe symptoms. Scores above 15 indicate clinical insomnia, and scores above 22 indicate severe symptoms.

GroupValue95% CI
CBTI-9.7± 4.42
ABTI-4.72± 4.5

Sponsor's own description

The purpose of this clinical trial is to assess the relative efficacy of two non-pharmacological interventions for insomnia in Veterans suffering from chronic mild traumatic brain injury (mTBI).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Perspective: Cognitive Behavioral Therapy for Insomnia Is a Promising Intervention for Mild Traumatic Brain Injury.
    Dietch JR, Furst AJ. · · 2020 · cited 6× · PMID 33117253 · DOI 10.3389/fneur.2020.530273

Verify or expand the search:

Other trials of CBT-I

Trials testing the same drug.

Other recruiting trials for Insomnia

Currently open trials in the same condition.

Other VA Office of Research and Development trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03261674.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing