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NCT03256357
Constraint-Induced Movement Therapy and Action Observation Training in Children With Unilateral Cerebral Palsy
NA trial testing Constraint-induced movement therapy in Cerebral Palsy in 44 participants. Completed in 28 February 2018.
28 February 2018
Quick facts
| Lead sponsor | KU Leuven |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 44 |
| Start date | 1 January 2014 |
| Primary completion | 28 February 2018 |
| Estimated completion | 28 February 2018 |
| Sites | 1 location across Belgium |
Drugs / interventions tested
- Constraint-induced movement therapy
- Action observation training
- Placebo observation training
Conditions studied
- Cerebral Palsy — all drugs for Cerebral Palsy →
Sponsor
KU Leuven — full company profile →
Who can join
Adults 5 to 12, any sex, with Cerebral Palsy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A randomized, controlled, and evaluator-blinded trail will be carried out comparing CIMT with or without AOT on sensorimotor outcome in children with unilateral CP aged 5 to 12 years. Additionally the potential role of neurological factors, including the anatomical characterization of the brain lesion, structural/functional connectivity and cortical reorganization, on treatment response will be investigated.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Randomized controlled trial combining constraint-induced movement therapy and action-observation training in unilateral cerebral palsy: clinical effects and influencing factors of treatment response.
Simon-Martinez C, Mailleux L, Hoskens J, Ortibus E, et al · · 2020 · cited 21× · PMID 32031542 · DOI 10.1177/1756286419898065 -
Effects of combining constraint-induced movement therapy and action-observation training on upper limb kinematics in children with unilateral cerebral palsy: a randomized controlled trial.
Simon-Martinez C, Mailleux L, Jaspers E, Ortibus E, et al · · 2020 · cited 19× · PMID 32591590 · DOI 10.1038/s41598-020-67427-2 -
Combining constraint-induced movement therapy and action-observation training in children with unilateral cerebral palsy: a randomized controlled trial.
Simon-Martinez C, Mailleux L, Ortibus E, Fehrenbach A, et al · · 2018 · cited 17× · PMID 30064396 · DOI 10.1186/s12887-018-1228-2 -
Randomized controlled trial combining constraint-induced movement therapy and action-observation training in unilateral cerebral palsy: clinical effects and influencing factors of treatment response
Simon-Martinez C, Mailleux L, Hoskens J, Ortibus E, et al · · 2019 · DOI 10.1101/19009472
Verify or expand the search:
- PubMed search for NCT03256357
- Europe PMC full search
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Related trials
Other trials of Constraint-induced movement therapy
Trials testing the same drug.
- NCT07458503 — tDCS Combined With Constraint-Induced Therapy in Post-Stroke Upper Limb Rehabilitation · NA · not yet recruiting
- NCT06485583 — Comparison Between the Efficacy of CIMT and NDT Along With Conventional Physiotherapy Treatment on Upper Extremity Rehab · NA · not yet recruiting
- NCT03754166 — Feasibility of Constraint-induced Therapy Combined With Visual-spatial Cueing Strategy in Patients With Acute Stroke · NA · terminated
- NCT03858335 — Therapeutic Effects of Constraint-Induced Movement Therapy on Young Children With Cerebral Palsy · NA · completed
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Currently open trials in the same condition.
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Other KU Leuven trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03256357 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by KU Leuven
- Last refreshed: 28 October 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03256357.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing