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NCT07458503: tDCS-CIT Strok
tDCS Combined With Constraint-Induced Therapy in Post-Stroke Upper Limb Rehabilitation
NA trial testing transcranial direct current stimulation (tDCS) in Stroke in 40 participants. Not yet recruiting.
15 December 2026
Quick facts
| Lead sponsor | Universidade do Estado do Pará |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 15 April 2026 |
| Primary completion | 15 December 2026 |
| Estimated completion | 10 April 2027 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- transcranial direct current stimulation (tDCS)
- Constraint-induced movement therapy
Conditions studied
- Stroke — all drugs for Stroke →
- Upper Limb Motor Impairment — all drugs for Upper Limb Motor Impairment →
- Post-Stroke Hemiparesis — all drugs for Post-Stroke Hemiparesis →
Sponsor
Universidade do Estado do Pará
Who can join
Adults 40 to 80, any sex, with Stroke or Upper Limb Motor Impairment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this clinical trial is to evaluate the effects of transcranial direct current stimulation (tDCS) combined with constraint-induced therapy (CIT) on upper limb motor recovery in individuals after stroke. The main questions it aims to answer are: Does the combination of tDCS and CIT improve upper limb motor function compared to CIT alone? Does the combined intervention promote changes in muscle morphology and electromyographic activity? Researchers will compare the group receiving tDCS combined with constraint-induced therapy to the group receiving constraint-induced therapy alone to determine whether the addition of cortical neuromodulation enhances motor recovery outcomes. This is a randomized, controlled, and blinded clinical trial in which participants will be divided into two groups: one group will receive tDCS combined with CIMT, and the other will undergo only CIMT. The protocol will include 18 sessions over six weeks, three times a week. Clinical and instrumental assessments will be performed before, during, and after the intervention, including the Fugl-Meyer scale for the upper limb, musculoskeletal ultrasound for morphological analysis, and surface electromyography for muscle activity assessment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07458503
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Stroke
Currently open trials in the same condition.
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- NCT07494890 — Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment · NA · recruiting
- NCT07356011 — Exoskeleton for Balance · NA · recruiting
- NCT07523503 — Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in · NA · recruiting
- NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting
Other Universidade do Estado do Pará trials
Trials by the same sponsor.
- NCT07046208 — Effects os Physiotherapeutic Rehabilitation on Function Autonomic and Inflammatory in Patients With Long Covid · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07458503 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidade do Estado do Pará
- Last refreshed: 9 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07458503.
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