Last reviewed · How we verify
NCT03249025
Lidocaine-Ketamine for Management of Chronic Pain
NA trial testing Lidocaine in Chronic Pain Syndrome in 72 participants. Status unknown.
1 September 2018
Quick facts
| Lead sponsor | Hamilton Health Sciences Corporation |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 72 |
| Start date | 1 September 2017 |
| Primary completion | 1 September 2018 |
| Estimated completion | 1 September 2018 |
Drugs / interventions tested
Conditions studied
- Chronic Pain Syndrome — all drugs for Chronic Pain Syndrome →
Sponsor
Hamilton Health Sciences Corporation — full company profile →
Who can join
Adults 18 to 90, any sex, with Chronic Pain Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Chronic pain is defined as 'an unpleasant sensory and emotional experience associated with actual or potential tissues damage, or described in terms of such damage". It is estimated that 1 in 5 Canadians experience chronic pain "Chronic pain is associated with the worst quality of life compared with other chronic diseases such as chronic lung or heart disease". Many of these problems are confined to a specific anatomic structure, and can be diagnosed and treated by injections, physical therapy, surgery, etc. Nonetheless, other individuals experience a more generalized pain. This condition has also resulted I depressed mood, bad relations with other people, sleep disturbances and poor quality of life. The condition is very difficult to manage, and multiple methods have been recommended. Therapeutic intravenous infusion may be considered as one of these methods. Patients come for infusions of non-opioid medications under medical supervision and in a scheduled fashion. Two most commonly used mediation are lidocaine and ketamine. Even though it is common to use multiple medications with complementary mechanisms of action to treat pain a combined lidocaine-ketamine infusion has never been studied Therefore, the purpose of this research study is to determine whether mixture of two medications (ketamine and lidocaine) infused intravenously 1 time per month for 6 months results in reduction of pain unpleasantness.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03249025
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Lidocaine
Trials testing the same drug.
- NCT07488832 — Intravenous Lidocaine Infusion in Lumbar Fusion Surgery · NA · recruiting
- NCT07445191 — Efficacy of Triamcinolone-Lidocaine Mix in Trigger Points Injection of Masseter Muscle: Double-blinded, Randomized Contr · Phase 2, PHASE3 · not yet recruiting
- NCT07422558 — Intravenous Nalbuphine Versus Lidocaine for Prevention of Propofol Injection Pain · NA · not yet recruiting
- NCT06923787 — Effect of Perioperative Intravenous Infusion of Lidocaine on the Postoperative Course and the Immune Response in Patient · Phase 2 · recruiting
- NCT07355049 — The Effect of Dexmedetomidine Versus Lidocaine on Emergence Agitation. · NA · not yet recruiting
Other recruiting trials for Chronic Pain Syndrome
Currently open trials in the same condition.
- NCT06929598 — Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents · NA · recruiting
- NCT06964243 — Protocol Assessment of Motor Cortex rTMS for Treating Neuropathic Pain · NA · recruiting
- NCT06903962 — Mind Body Intervention for Chronic Upper Extremity Pain (Repetitive Stress Injury) · NA · recruiting
- NCT06503562 — Chronic Nonspecific Neck Pain and Central Nervous System Focused Treatment Program · NA · recruiting
- NCT06387706 — The Development of a Gamified Web-based Pain Management Program (GAP) for Community-dwelling Older Adults With Chronic P · NA · recruiting
Other Hamilton Health Sciences Corporation trials
Trials by the same sponsor.
- NCT06567808 — Prevention of Infections in Cardiac Surgery (PICS): a Cluster-randomized Factorial Cross-over Trial · Phase 4 · not yet recruiting
- NCT07118696 — Evaluating a Shorter, Rifampicin-Based Treatment for People With Less Severe Tuberculosis Disease · Phase 3 · not yet recruiting
- NCT07027436 — Radiation Therapy Followed by Durvalumab (MEDI4736) and Tremelimumab And Surgery Versus Radiation Therapy Followed by Su · Phase 3 · not yet recruiting
- NCT06908694 — Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen Deprivation Therapy · Phase 4 · recruiting
- NCT06836024 — A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation · Phase 2, PHASE3 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03249025 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hamilton Health Sciences Corporation
- Last refreshed: 15 August 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03249025.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing