NCT03224650 is a clinical trial in Spinal Metastases, sponsored by Brigham and Women's Hospital.

Who is sponsoring NCT03224650?

NCT03224650 is sponsored by Brigham and Women's Hospital.

What condition does NCT03224650 study?

NCT03224650 studies Spinal Metastases.

Is NCT03224650 still recruiting?

NCT03224650 is currently completed. Last updated 2 March 2022.

Last reviewed 2022-03-02 · How we verify

NCT03224650

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Validation of Novel Predictive Score for Patients With Spinal Metastases

Completed Last updated 2 March 2022

What this trial tests

trial in Spinal Metastases in 219 participants. Completed in 31 January 2022.

Timeline

1 July 2017

Primary endpoint
13 July 2020

31 January 2022

Quick facts

Lead sponsor	Brigham and Women's Hospital
Status	Completed
Study type	OBSERVATIONAL
Enrollment	219
Start date	1 July 2017
Primary completion	13 July 2020
Estimated completion	31 January 2022
Sites	1 location across United States

Conditions studied

Spinal Metastases — all drugs for Spinal Metastases →

Sponsor

Brigham and Women's Hospital

Who can join

18 and older, any sex, with Spinal Metastases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators are prospectively validating a prognostic clinical tool that uses a patient's modified Bauer grade, ambulatory status, and pre-operative serum albumin to predict survival, post-treatment morbidity, and functional outcomes in patients with metastatic disease involving the spine.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Prospective comparison of the accuracy of the New England Spinal Metastasis Score (NESMS) to legacy scoring systems in prognosticating outcomes following treatment of spinal metastases.
Schoenfeld AJ, Ferrone ML, Blucher JA, Agaronnik N, et al · · 2022 · cited 29× · PMID 33741509 · DOI 10.1016/j.spinee.2021.03.007
Prospective comparison of one-year survival in patients treated operatively and nonoperatively for spinal metastatic disease: results of the prospective observational study of spinal metastasis treatment (POST).
Xiong GX, Collins JE, Ferrone ML, Schoenfeld AJ. · · 2023 · cited 4× · PMID 35181541 · DOI 10.1016/j.spinee.2022.02.004
Racial, ethnic, and socioeconomic disparities in clinical trial reporting for metastatic spine tumors: An exploration of North American studies.
Bangash AH, Fluss R, Eleswarapu AS, Fourman MS, et al · · 2025 · PMID 39969615 · DOI 10.1007/s10143-025-03343-1

Verify or expand the search:

Other recruiting trials for Spinal Metastases

Currently open trials in the same condition.

NCT06548061 — D20054;LITT for Spine Tumors · NA · recruiting
NCT06244264 — The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis · NA · recruiting
NCT06120426 — En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor · recruiting
NCT05575323 — Randomized Trial on Same-day SBRT and Surgical Stabilization for Symptomatic Spinal Metastases · NA · recruiting
NCT07429422 — SBRT Technique Implementation for Spinal Metastases Irradiation · NA · recruiting

Other Brigham and Women's Hospital trials

Trials by the same sponsor.

NCT07011758 — Dynamic Treatment Regimes for Opioid Use Disorder · Phase 2 · not yet recruiting
NCT06310018 — Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE · suspended
NCT04519177 — Randomized Trial of a Sleep Disorders Program on Firefighter Safety and Disability ... · NA · not yet recruiting
NCT06355986 — Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · NA · not yet recruiting
NCT06099275 — Evaluation of Hemodynamics in People With Untreated Preeclampsia Using Echocardiography · suspended

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03224650 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Brigham and Women's Hospital
Last refreshed: 2 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03224650.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing