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NCT03219125: ADIMOS

Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women

Completed Last updated 4 November 2022
What this trial tests

trial testing Dixon Magnetic Resonance Imaging in Fractures, Bone in 203 participants. Completed in 25 June 2021.

Timeline
16 October 2018
Primary endpoint
25 June 2021
25 June 2021

Quick facts

Lead sponsorUniversity Hospital, Lille
StatusCompleted
Study typeOBSERVATIONAL
Enrollment203
Start date16 October 2018
Primary completion25 June 2021
Estimated completion25 June 2021
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Lille

Who can join

Adults 50 to 90, female only, with Fractures, Bone or Bone Marrow Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose is to determine in a case-control study if an association exist between bone marrow adiposity and fragility fractures in post-menopausal women.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Bone Marrow Adiposity Alterations in Postmenopausal Women With Type 2 Diabetes Are Site-Specific.
    Badr S, Cotten A, Lombardo D, Ruschke S, et al · · 2024 · cited 4× · PMID 39381685 · DOI 10.1210/jendso/bvae161
  2. Marrow Adiposity Content and Composition Are Not Associated With Incident Fragility Fractures in Postmenopausal Women: The ADIMOS Fracture Study.
    Philippoteaux C, Badr S, Lombardo D, Cailliau E, et al · · 2025 · cited 1× · PMID 40071067 · DOI 10.1210/jendso/bvaf033
  3. Relationship between bone marrow adipose tissue and kidney function in postmenopausal women.
    Badr S, Cotten A, Mentaverri R, Lombardo D, et al · · 2023 · cited 1× · PMID 37711545 · DOI 10.1016/j.bonr.2023.101713
  4. Myosteatosis and bone marrow adiposity are not associated among postmenopausal women with fragility fractures.
    Badr S, Dapvril H, Lombardo D, Khizindar H, et al · · 2023 · PMID 37404309 · DOI 10.3389/fendo.2023.1178464

Verify or expand the search:

Other recruiting trials for Fractures, Bone

Currently open trials in the same condition.

Other University Hospital, Lille trials

Trials by the same sponsor.

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Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing