Last reviewed · How we verify
NCT03199027: TRAC
Timing of Referral to Adherence Clubs for Antiretroviral Therapy
NA trial testing Adherence Club in Hiv in 220 participants. Completed in 31 January 2019.
6 October 2018
Quick facts
| Lead sponsor | University of Cape Town |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | health services research |
| Enrollment | 220 |
| Start date | 18 January 2017 |
| Primary completion | 6 October 2018 |
| Estimated completion | 31 January 2019 |
| Sites | 1 location across South Africa |
Drugs / interventions tested
- Adherence Club
Conditions studied
- Hiv — all drugs for Hiv →
Sponsor
University of Cape Town
Who can join
18 and older, any sex, with Hiv. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Following the announcement of the global "90-90-90" strategy, there is a huge need in South Africa for effective well-developed scaled-up models of ART (anti-retroviral therapy) delivery that aim to improve patient adherence and viral suppression. The ART adherence club is one such model of service delivery. The investigators are conducting a pragmatic randomised control trial to compare virological outcomes 12 months post-ART initiation between arms: individuals referred to the Adherence club at 4 months post-ART initiation (early referral) and individuals referred to the Adherence club at 12 months post-ART initiation (delayed referral). Individuals with delayed Adherence club referral will continue to attend the ART clinic as per the Standard-of-Care.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Accuracy of measures for antiretroviral adherence in people living with HIV.
Smith R, Villanueva G, Probyn K, Sguassero Y, et al · · 2022 · cited 34× · PMID 35871531 · DOI 10.1002/14651858.cd013080.pub2 -
Virologic outcomes after early referral of stable HIV-positive adults initiating ART to community-based adherence clubs in Cape Town, South Africa: A randomised controlled trial.
Odayar J, Malaba TR, Allerton J, Kabanda S, et al · · 2022 · cited 6× · PMID 36378660 · DOI 10.1371/journal.pone.0277018
Verify or expand the search:
- PubMed search for NCT03199027
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hiv
Currently open trials in the same condition.
- NCT06001814 — Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV · NA · recruiting
- NCT06999928 — Enhanced Mentor Mother Strategy for Pregnant and Postpartum Women Living With HIV · NA · recruiting
- NCT06006143 — Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2 · Phase 2 · active not recruiting
- NCT07076043 — Multi-product PrEP Delivery to Young Women Seeking Reproductive Health Services and Coverage of HIV Prevention · Phase 4 · recruiting
- NCT06389565 — Change My Story Task Shifted Mental Health Intervention · NA · recruiting
Other University of Cape Town trials
Trials by the same sponsor.
- NCT06997328 — '5 Rs to Rescue' A Cluster Trial With an Embedded Process Evaluation · recruiting
- NCT06431321 — Evaluation of a 2-session Parent Training Programme for Caregivers of Younger Children in Zimbabwe · NA · not yet recruiting
- NCT06051526 — The African Critical Illness Outcomes Study · completed
- NCT05723484 — Comparing a Novel Point-of-care Cytokine Biomarker Lateral Flow Test With Nucleic Acid Amplification Tests for Detection · completed
- NCT05681871 — South African Paediatric Surgical Outcomes Study 2 · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03199027 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Cape Town
- Last refreshed: 4 September 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03199027.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing