NCT05723484 (GIFT) is a clinical trial of GIFT Device in STI, sponsored by University of Cape Town.

Who is sponsoring NCT05723484?

NCT05723484 is sponsored by University of Cape Town.

What drugs are being tested in NCT05723484?

Interventions in NCT05723484: GIFT Device.

Is NCT05723484 still recruiting?

NCT05723484 is currently completed. Last updated 6 August 2025.

Last reviewed 2025-08-06 · How we verify

NCT05723484: GIFT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparing a Novel Point-of-care Cytokine Biomarker Lateral Flow Test With Nucleic Acid Amplification Tests for Detection of Sexually Transmitted Infections and Bacterial Vaginosis

Completed Last updated 6 August 2025

What this trial tests

trial testing GIFT Device in STI in 675 participants. Completed in 31 December 2023.

Timeline

1 June 2023

Primary endpoint
31 December 2023

31 December 2023

Quick facts

Lead sponsor	University of Cape Town
Status	Completed
Study type	OBSERVATIONAL
Enrollment	675
Start date	1 June 2023
Primary completion	31 December 2023
Estimated completion	31 December 2023
Sites	3 locations across Madagascar, Zimbabwe, South Africa

Drugs / interventions tested

GIFT Device

Conditions studied

STI — all drugs for STI →

Sponsor

University of Cape Town

Who can join

Adults 18 to 35, female only, with STI. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

1. To evaluate the performance of a lateral flow POC test, namely the Genital InFlammation Test (GIFT), for identifying women with inflammatory STIs and BV, who are at higher risk of HIV infection and reproductive complications; 2. To evaluate how the GIFT device can be integrated in a feasible, acceptable, and cost-effective way into routine care.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Novel point-of-care cytokine biomarker lateral flow test for the screening for sexually transmitted infections and bacterial vaginosis: study protocol of a multicentre multidisciplinary prospective observational clinical study to evaluate the performance and feasibility of the Ge
Ramboarina S, Crucitti T, Gill K, Bekker LG, et al · · 2024 · cited 4× · PMID 38692732 · DOI 10.1136/bmjopen-2024-084918
A Novel Point-Of-Care Cytokine Biomarker Lateral Flow Test for the Screening for Sexually Transmitted Infections and Bacterial Vaginosis: Study Protocol of a Multi-Centre Multi-Disciplinary Prospective Clinical Study to Evaluate the Performance and Feasibility of the Genital Infl
Ramboarina S, Crucitti T, Gill K, Bekker L, et al · · 2023 · DOI 10.21203/rs.3.rs-3675671/v1

Verify or expand the search:

Other recruiting trials for STI

Currently open trials in the same condition.

NCT07186244 — Prevention ICONA Dedicated Ensemble · recruiting
NCT05856942 — Hybrid Evaluation of a Home-based HIV Pre-exposure Prophylaxis Program · NA · recruiting
NCT04832477 — Assessing the PrEP Care Cascade Among Black Men and Transwomen in the Southeastern US · NA · active not recruiting

Other University of Cape Town trials

Trials by the same sponsor.

NCT06997328 — '5 Rs to Rescue' A Cluster Trial With an Embedded Process Evaluation · recruiting
NCT06431321 — Evaluation of a 2-session Parent Training Programme for Caregivers of Younger Children in Zimbabwe · NA · not yet recruiting
NCT06051526 — The African Critical Illness Outcomes Study · completed
NCT05681871 — South African Paediatric Surgical Outcomes Study 2 · Phase 4 · completed
NCT06466642 — B.R.A.I.N in People Living With HIV Study · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05723484 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Cape Town
Last refreshed: 6 August 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05723484.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing