NCT03191253: CHEFS

Changing Health Through Food Support (CHEFS) Program

Completed NA Last updated 21 March 2022

What this trial tests

NA trial testing Medically-appropriate meals and groceries in HIV/AIDS in 191 participants. Completed in 28 September 2017.

Timeline

6 July 2016

Primary endpoint
28 September 2017

28 September 2017

Quick facts

Lead sponsor	University of California, San Francisco
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	191
Start date	6 July 2016
Primary completion	28 September 2017
Estimated completion	28 September 2017

Drugs / interventions tested

• Medically-appropriate meals and groceries

Conditions studied

• HIV/AIDS — all drugs for HIV/AIDS →

Sponsor

University of California, San Francisco

Who can join

18 and older, any sex, with HIV/AIDS. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

UCSF and Project Open Hand (POH), a community based organization in San Francisco which provides meals and groceries to chronically ill clients in the Bay Area, have partnered to conduct an initial randomized controlled trial (RCT) of the Changing Health through Food Support (CHEFS) pilot intervention implemented by POH. The intervention consists of providing comprehensive, medically-appropriate food support, individual nutritional counseling, and group-based nutritional education over 6 months to low-income clients who have been diagnosed with HIV in order to improve their viral load and health-related quality of life (primary outcomes) as well as depression, ART adherence, food security and diet quality (secondary outcomes). We will randomize 200 participants to the intervention (n=100) or control (n=100). Participants will be followed for 6 months. The investigators will assess outcomes at baseline and 6-month follow-up using a quantitative survey and blood draws. In addition, the investigators will conduct a qualitative study at follow-up in a subset of participants to understand perceived impacts, barriers and facilitators.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Dietary advice with or without oral nutritional supplements for disease-related malnutrition in adults.
   Baldwin C, de van der Schueren MA, Kruizenga HM, Weekes CE. · · 2021 · cited 24× · PMID 34931696 · DOI 10.1002/14651858.cd002008.pub5
2. Food Is Medicine for Human Immunodeficiency Virus: Improved Health and Hospitalizations in the Changing Health Through Food Support (CHEFS-HIV) Pragmatic Randomized Trial.
   Palar K, Sheira LA, Frongillo EA, O'Donnell AA, et al · · 2025 · cited 6× · PMID 38696724 · DOI 10.1093/infdis/jiae195