NCT03190486

Perception of Baby's Painful Cry in fMRI

Completed NA Last updated 10 October 2018

What this trial tests

NA trial testing functional Magnetic Resonance Imaging (fMRI) in Magnetic Resonance Imaging in 80 participants. Completed in 5 July 2018.

Timeline

24 July 2017

Primary endpoint
5 July 2018

5 July 2018

Quick facts

Lead sponsor	Centre Hospitalier Universitaire de Saint Etienne
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	80
Start date	24 July 2017
Primary completion	5 July 2018
Estimated completion	5 July 2018
Sites	1 location across France

Drugs / interventions tested

• functional Magnetic Resonance Imaging (fMRI)

Conditions studied

• Magnetic Resonance Imaging — all drugs for Magnetic Resonance Imaging →
• Neuronal Activity — all drugs for Neuronal Activity →

Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Who can join

Adults 18 to 50, any sex, with Magnetic Resonance Imaging or Neuronal Activity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Crying is the primary signaling strategy available to the human newborn for eliciting parental care. Yet, the investigators only have superficial understanding of the information carried by cries, and how this information is perceived by parents. Using modern tools of sound processing and functional Magnetic Resonance Imaging (fMRI) experiment, this study aims to investigate cry-induced brain activation in adult depending on the cry's acoustic properties expressing various degrees of stress and distress levels. For that, Adults will be tested inside a fMRI magnet to determine their brain activations elicited by different babies cries according to whether the cry was evoked in a pain situation or not. The cerebral activity will be investigated in relation to acoustic features of cries (e.g. with pitch and/or roughness variations). To test if the gender or parentally of adult listeners influence their perceptions and brain responses, the task will be applied to 2 different groups (men and women not-parents). The hypothesis is that the brain of adult listeners will be able to discriminate adequately the intensity of the pain mediated by the cries. This process should involve brain areas such as the insular and the orbito frontal cortex that are known to participate in the integration of pain intensity and pain controls. The experiment should also determine which one of the acoustic features is able to transmit pain and to recruit brain areas involved in pain processes.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.