Who is sponsoring NCT03177837?

NCT03177837 is sponsored by University of Zurich.

What drugs are being tested in NCT03177837?

Interventions in NCT03177837: ACETAZOLAMIDE oral capsule, Placebo oral capsule.

What condition does NCT03177837 study?

NCT03177837 studies Chronic Obstructive Pulmonary Disease.

Is NCT03177837 still recruiting?

NCT03177837 is currently completed. Last updated 16 August 2019.

Last reviewed 2019-08-16 · How we verify

NCT03177837

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude

Completed Phase 4 Last updated 16 August 2019

What this trial tests

Phase 4 trial testing ACETAZOLAMIDE oral capsule in Chronic Obstructive Pulmonary Disease in 176 participants. Completed in 2 August 2018.

Timeline

24 May 2017

Primary endpoint
2 August 2018

2 August 2018

Quick facts

Lead sponsor	University of Zurich
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	176
Start date	24 May 2017
Primary completion	2 August 2018
Estimated completion	2 August 2018
Sites	1 location across Kyrgyzstan

Drugs / interventions tested

ACETAZOLAMIDE oral capsule — full drug profile →
Placebo oral capsule

Conditions studied

Chronic Obstructive Pulmonary Disease — all drugs for Chronic Obstructive Pulmonary Disease →

Sponsor

University of Zurich

Who can join

Adults 18 to 75, any sex, with Chronic Obstructive Pulmonary Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this trial, the investigators will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on exercise performance at altitude in patients with COPD.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effects of acetazolamide on exercise performance in patients with COPD going to high altitude: randomised controlled trial.
Kind RF, Furian M, Buergin A, Scheiwiller PM, et al · · 2025 · cited 3× · PMID 39834599 · DOI 10.1183/23120541.00767-2024

Verify or expand the search:

Other trials of ACETAZOLAMIDE oral capsule

Trials testing the same drug.

NCT07517068 — The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude · EARLY_PHASE1 · active not recruiting
NCT03537924 — Effect of Acetazolamide on Right Heart Function During Exercise in Lowlanders Older Than 40 Years at Altitude · Phase 4 · unknown
NCT03540914 — Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders Older Than 40 Years at Altitude. · Phase 4 · unknown
NCT03539367 — Effect of Acetazolamide on Lung Water Content by Ultrasound in Lowlanders Older Than 40 Years at Altitude · Phase 4 · unknown
NCT03540901 — Effect of Acetazolamide on Lung Water Content by Ultrasound in Patients With Respiratory Disease at Altitude · Phase 4 · completed

Other recruiting trials for Chronic Obstructive Pulmonary Disease

Currently open trials in the same condition.

NCT06749262 — Inclined Versus Standard Exercise for COPD Patients · NA · recruiting
NCT07406659 — Different Inspiratory Muscle Trainings in Patients With COPD · NA · recruiting
NCT07051707 — Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD · NA · recruiting
NCT07418736 — A Phase II Study of CM326 in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease · Phase 2 · recruiting
NCT07069829 — Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo · recruiting

Other University of Zurich trials

Trials by the same sponsor.

NCT07485699 — Soy Processing and Food Allergy · NA · not yet recruiting
NCT07516912 — Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland · not yet recruiting
NCT07473115 — Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustm · not yet recruiting
NCT07524023 — Emotional-distress-based Integrated Care Programme in Patients With Stable COPD · NA · recruiting
NCT06481982 — Value of Advanced MRI Techniques in the Assessment of Endometriosis · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03177837 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Zurich
Last refreshed: 16 August 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03177837.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing