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NCT03175302: PRECEDE

PREsurgical Cognitive Evaluation Via Digital clockfacEdrawing

Recruiting now Last updated 31 July 2025
What this trial tests

trial testing digital cognitive testing in Cognitive Dysfunction in 25,240 participants. Currently enrolling.

Timeline
28 June 2018
Primary endpoint
31 May 2027
31 May 2027

Quick facts

Lead sponsorUniversity of Florida
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment25,240
Start date28 June 2018
Primary completion31 May 2027
Estimated completion31 May 2027
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Florida

Who can join

65 and older, any sex, with Cognitive Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study leverages a modernized digital version of a well-known cognitive screening tool to examine pre and post operative cognitive function after surgery in adults age 65 years or more. Machine learning algorithms will be applied to the hospital wide standard of care cognitive metric to identify risk for post-operative cognitive complications.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Surgical data science - from concepts toward clinical translation.
    Maier-Hein L, Eisenmann M, Sarikaya D, März K, et al · · 2022 · cited 158× · PMID 34879287 · DOI 10.1016/j.media.2021.102306
  2. Variational autoencoder provides proof of concept that compressing CDT to extremely low-dimensional space retains its ability of distinguishing dementia.
    Bandyopadhyay S, Dion C, Libon DJ, Price C, et al · · 2022 · cited 10× · PMID 35568709 · DOI 10.1038/s41598-022-12024-8
  3. Explainable semi-supervised deep learning shows that dementia is associated with small, avocado-shaped clocks with irregularly placed hands.
    Bandyopadhyay S, Wittmayer J, Libon DJ, Tighe P, et al · · 2023 · cited 8× · PMID 37149670 · DOI 10.1038/s41598-023-34518-9

Verify or expand the search:

Other recruiting trials for Cognitive Dysfunction

Currently open trials in the same condition.

Other University of Florida trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03175302.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing