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NCT03159000
A Research Study of Greater Occipital Nerve Block as a Treatment for Acute Migraine Attacks
Phase 4 trial testing Saline in Migraine. Withdrawn.
31 December 2017
Quick facts
| Lead sponsor | Thomas Jefferson University |
|---|---|
| Phase | Phase 4 |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Start date | 1 May 2017 |
| Primary completion | 31 December 2017 |
| Estimated completion | 30 June 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Saline
- lidocaine/bupivacaine
Conditions studied
- Migraine — all drugs for Migraine →
Sponsor
Thomas Jefferson University
Who can join
Adults 18 to 80, any sex, with Migraine. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Several observational studies have shown improvement in episodic migraine with the use of greater occipital nerve block as an acute therapy, and a recent placebo controlled trial did not show a decrease in frequency of episodic or chronic migraine; however, there has never been a placebo controlled trial to investigate the efficacy of GONB as an acute treatment for headache, and there has been no determination of guidelines for selection of patients who would be most likely to respond to GONB. In light of the above, the investigators propose a double-blind, placebo-controlled, randomized trial examining the use of GONB with lidocaine/bupivocaine in patients with an acute episodic migraine. The results of this trial are expected to guide more appropriate therapeutic management of these participants and the optimal use of this procedure. 50 subjects will be entered into this study. This study is being conducted at Thomas Jefferson University only.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03159000
- Europe PMC full search
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- ESMO Meeting Library
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Other recruiting trials for Migraine
Currently open trials in the same condition.
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Other Thomas Jefferson University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03159000 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Thomas Jefferson University
- Last refreshed: 26 November 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03159000.
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