Last reviewed · How we verify

NCT03153020: OBSTACLE

Determinants of Adherence to Post-stroke/Transient Ischemic Attack Secondary Prevention Treatment: Cohort Study in the Rhône

Completed Last updated 25 November 2025
What this trial tests

trial testing Patients with stroke or transient ischemic attack in Stroke in 633 participants. Completed in 31 December 2019.

Timeline
11 September 2017
Primary endpoint
31 December 2018
31 December 2019

Quick facts

Lead sponsorHospices Civils de Lyon
StatusCompleted
Study typeOBSERVATIONAL
Enrollment633
Start date11 September 2017
Primary completion31 December 2018
Estimated completion31 December 2019
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Hospices Civils de Lyon — full company profile →

Who can join

18 and older, any sex, with Stroke or Transient Ischemic Attack. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The effectiveness of emergency management of acute ischemic stroke has improved considerably in recent years with thrombolysis and more recently thrombectomy. This improvement is accompanied by an increase in the number of stroke survivors. One of the major issues for these ever-increasing survivors is the prevention of recurrence. According to data from the 3 French registries, more than 20% of patients have at least one recurrence. Secondary prevention treatment has demonstrated his efficacy to prevent stroke recurrence. This evolution justifies identifying factors associated with adherence to secondary prevention treatment, measured at 1 year post-stroke / transient ischemic attack (TIA), in patients included in the STROKE 69 cohort.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. A Qualitative Study of Barriers and Facilitators to Adherence to Secondary Prevention Medications Among French Patients Suffering from Stroke and Transient Ischemic Attack.
    Viprey M, Gouillet M, Puppo C, Termoz A, et al · · 2020 · cited 3× · PMID 32801652 · DOI 10.2147/ppa.s257323
  2. Determinants of adherence to post-stroke/transient ischemic attack secondary prevention medications: A cohort study.
    Hoarau D, Ramos I, Termoz A, Fernandez V, et al · · 2024 · cited 2× · PMID 38953278 · DOI 10.1111/ene.16395
  3. European Stroke Organisation Conference: Abstracts
    · 2018

Verify or expand the search:

Other recruiting trials for Stroke

Currently open trials in the same condition.

Other Hospices Civils de Lyon trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03153020.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing