NCT03150667 (CPRS-CKD) is a Phase 4 clinical trial of Ticagrelor in Chronic Kidney Diseases, sponsored by North Texas Veterans Healthcare System.

Who is sponsoring NCT03150667?

NCT03150667 is sponsored by North Texas Veterans Healthcare System.

What drugs are being tested in NCT03150667?

Interventions in NCT03150667: Ticagrelor, Clopidogrel.

What condition does NCT03150667 study?

NCT03150667 studies Chronic Kidney Diseases, Acute Coronary Syndrome.

Is NCT03150667 still recruiting?

NCT03150667 is currently status unknown. Last updated 25 May 2018.

Last reviewed 2018-05-25 · How we verify

NCT03150667: CPRS-CKD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Study Comparing Treatment Effectiveness of Guideline Indicated APT for ACS in Patients With CKD

Status unknown Phase 4 Last updated 25 May 2018

What this trial tests

Phase 4 trial testing Ticagrelor in Chronic Kidney Diseases in 220 participants. Status unknown.

Timeline

10 April 2017

Primary endpoint
30 April 2019

30 April 2020

Quick facts

Lead sponsor	North Texas Veterans Healthcare System
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	220
Start date	10 April 2017
Primary completion	30 April 2019
Estimated completion	30 April 2020
Sites	2 locations across United States

Drugs / interventions tested

Ticagrelor (ticagrelor) — full drug profile →
Clopidogrel (clopidogrel) — full drug profile →

Conditions studied

Chronic Kidney Diseases — all drugs for Chronic Kidney Diseases →
Acute Coronary Syndrome — all drugs for Acute Coronary Syndrome →

Sponsor

North Texas Veterans Healthcare System

Who can join

18 and older, any sex, with Chronic Kidney Diseases or Acute Coronary Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To compare clinical outcomes in patients with chronic kidney disease (CKD) presenting with an acute coronary syndrome (ACS) treated with clopidogrel or ticagrelor (both FDA approved and guideline indicated drugs for treating these patients upstream managed medically or with coronary revascularization).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Antiplatelet agents for chronic kidney disease.
Natale P, Palmer SC, Saglimbene VM, Ruospo M, et al · · 2022 · cited 21× · PMID 35224730 · DOI 10.1002/14651858.cd008834.pub4

Verify or expand the search:

Other trials of Ticagrelor

Trials testing the same drug.

NCT06451198 — IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly Patients With Acute Coronary Syndrome · Phase 4 · recruiting
NCT07358416 — Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery. · active not recruiting
NCT06584812 — Study to Assess Pharmacokinetics, Pharmacodynamics and Safety of Tiprogrel in Healthy Subjects · Phase 1 · completed
NCT06554821 — A Study to Investigate the Effect of Oral Ticagrelor on the Pharmacokinetics of Oral Rosuvastatin When Given in Healthy · Phase 1 · completed
NCT06301776 — A Prospective, Experimental, Multicenter, Open-label, Randomized, Controlled Trial of 3-month Dual Antiplatelet Therapy · NA · recruiting

Other recruiting trials for Chronic Kidney Diseases

Currently open trials in the same condition.

NCT06593392 — Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus · Phase 2 · recruiting
NCT07358572 — Eye-Brain-Kidney in CKD · recruiting
NCT06463483 — Automated Insulin Delivery in Adults With Advanced Kidney Disease · NA · recruiting
NCT06927024 — Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD) · NA · recruiting
NCT07115953 — Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension · NA · recruiting

Other North Texas Veterans Healthcare System trials

Trials by the same sponsor.

NCT03929939 — Neural Control and Cardiac-Vascular Function in Women With PTSD (VA Psychological Assessment) · NA · completed
NCT02387658 — Outcomes in Femoropopliteal Disease Stratified by Translesional Pressure Gradient · completed
NCT00781573 — Study of Optimal Clopidogrel Duration in Patients Receiving Drug Eluting Stents (SCORE Trial) · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03150667 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by North Texas Veterans Healthcare System
Last refreshed: 25 May 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03150667.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing