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NCT06301776
A Prospective, Experimental, Multicenter, Open-label, Randomized, Controlled Trial of 3-month Dual Antiplatelet Therapy Followed by Ticagrelor Versus 6-month Dual Antiplatelet Therapy Followed by Ticagrelor After Implanting Bridge
NA trial testing Ticagrelor in Brain Disease in 560 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | The Fourth Affiliated Hospital of China Medical University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 560 |
| Start date | 5 December 2023 |
| Primary completion | 31 December 2025 |
| Estimated completion | 30 June 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Ticagrelor (ticagrelor) — full drug profile →
Conditions studied
- Brain Disease — all drugs for Brain Disease →
- Vertebral Artery Stenosis — all drugs for Vertebral Artery Stenosis →
Sponsor
The Fourth Affiliated Hospital of China Medical University
Who can join
Adults 18 to 80, any sex, with Brain Disease or Vertebral Artery Stenosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To compare the incidence of the composite endpoints of non-fatal ischaemic stroke, transient ischaemia (TIA) and all-cause mortality at 12-month follow-up after implantation of Bridge for the treatment of symptomatic vertebral artery stenosis in subjects who had been taking different durations of dual-antiplatelet therapy (3 vs 6 months) and ticagrelor monotherapy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06301776
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06584812 — Study to Assess Pharmacokinetics, Pharmacodynamics and Safety of Tiprogrel in Healthy Subjects · Phase 1 · completed
- NCT06554821 — A Study to Investigate the Effect of Oral Ticagrelor on the Pharmacokinetics of Oral Rosuvastatin When Given in Healthy · Phase 1 · completed
- NCT06088433 — Ticagrelor Single Antiplatelet Therapy in Patients With High Risk of Bleeding After DCB for Coronary Small Vessel Diseas · Phase 4 · unknown
Other recruiting trials for Brain Disease
Currently open trials in the same condition.
- NCT06615973 — Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke · recruiting
- NCT04383808 — Clinical Translation of a Novel Brain PET Insert for Simultaneous PET/MR · NA · recruiting
- NCT07253974 — Prospective Evaluation of Atrial Fibrillation-Related Stroke Patients in Rehabilitation Program (PEARL), an Observationa · recruiting
- NCT07056348 — Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function · NA · recruiting
- NCT04286516 — Brain Connections for Arm Movement After Stroke · NA · recruiting
Other The Fourth Affiliated Hospital of China Medical University trials
Trials by the same sponsor.
- NCT07339306 — A Novel Fluorescent Ductal Needle for Localization and Sampling of Micro Lesions in Breast Ducts · NA · recruiting
- NCT06994416 — A Novel Fluorescent Ductal Needle for Localization and Sampling of High-risk Breast Micro Lesions · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06301776 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Fourth Affiliated Hospital of China Medical University
- Last refreshed: 8 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06301776.
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