Who is sponsoring NCT03149692?

NCT03149692 is sponsored by University of Stellenbosch.

What drugs are being tested in NCT03149692?

Interventions in NCT03149692: Penile allograft transplantation.

What condition does NCT03149692 study?

NCT03149692 studies Penile Amputation.

Is NCT03149692 still recruiting?

NCT03149692 is currently completed. Last updated 6 October 2021.

Last reviewed 2021-10-06 · How we verify

NCT03149692

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Penile Transplant Study

Completed NA Last updated 6 October 2021

What this trial tests

NA trial testing Penile allograft transplantation in Penile Amputation in 2 participants. Completed in 11 December 2020.

Timeline

11 November 2011

Primary endpoint
11 December 2019

11 December 2020

Quick facts

Lead sponsor	University of Stellenbosch
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	2
Start date	11 November 2011
Primary completion	11 December 2019
Estimated completion	11 December 2020
Sites	1 location across South Africa

Drugs / interventions tested

Penile allograft transplantation

Conditions studied

Penile Amputation — all drugs for Penile Amputation →

Sponsor

University of Stellenbosch

Who can join

Adults 18 to 40, male only, with Penile Amputation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

One case of unsuccessful penile transplantation has been reported from China. The patient had suffered an industrial machine accident and lost his penis to the level of the pubic skin. Unfortunately the patient's wife insisted at about two weeks post-operatively that the organ be removed. At the time of surgical removal the penis was viable, except for a degree of superficial skin necrolysis. This has sparked debate on ethical issues regarding penile transplantation. South Africa is uniquely positioned in Sub-Saharan Africa and worldwide with relatively advanced medical services and a high prevalence of ritual circumcision practice with reports of high morbidity and mortality in the last 20 years. The substantial number of young men left with a severe penile defect or complete loss of the penis \[9\] creates a possible place for penile allograft transplantation as a treatment option.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Living with someone else's penis: The lived experiences of two South African penile allograft recipients: A descriptive phenomenological study.
van der Merwe A, Toefy Y, Moosa MR, van Deventer H, et al · · 2021 · cited 7× · PMID 34527236 · DOI 10.1016/j.amsu.2021.102794

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03149692 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Stellenbosch
Last refreshed: 6 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03149692.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing