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NCT06796413
Loop Resection or Cold-cup Biopsy? A Study Comparing the Accuracy of Muscle Samples During Bladder Tumor Surgery
NA trial testing Loop Resection or Cold-cup biopsy in Bladder Cancer in 120 participants. Completed in 1 July 2024.
23 May 2024
Quick facts
| Lead sponsor | University of Stellenbosch |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | diagnostic |
| Enrollment | 120 |
| Start date | 14 July 2022 |
| Primary completion | 23 May 2024 |
| Estimated completion | 1 July 2024 |
| Sites | 1 location across South Africa |
Drugs / interventions tested
- Loop Resection or Cold-cup biopsy
Conditions studied
- Bladder Cancer — all drugs for Bladder Cancer →
- Bladder Cancer Stage I — all drugs for Bladder Cancer Stage I →
- TURBT — all drugs for TURBT →
Sponsor
University of Stellenbosch
Who can join
Eligibility, any sex, with Bladder Cancer or Bladder Cancer Stage I. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this report the investigators compared two deep muscle sampling methods (Loop resection and Cold-Cup Biopsy) during endoscopic resection of bladder tumors for patients with suspected bladder cancer in Tygerberg hospital. The investigators found that both sampling methods are equal effective with regards to muscle representation, regardless of surgeon experience. An important finding is that Loop Resection produced less tissue artefacts in the deep muscle specimen for the more experienced surgeons, while there was no difference for less experienced surgeons. The investigators thus conclude that - from a practical point of view - Loop Resection should be the deep muscle sampling method of choice.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06796413
- Europe PMC full search
- ASCO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06796413 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Stellenbosch
- Last refreshed: 28 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06796413.
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