NCT03147703: ONTIME-MIC

Timing of Food Intake Impacts Daily Rhythms of Human Saliva Microbiota

Completed NA Last updated 22 April 2021

What this trial tests

NA trial testing Food Timing in Healthy Women in 10 participants. Completed in 31 July 2015.

Timeline

1 June 2015

Primary endpoint
1 July 2015

31 July 2015

Quick facts

Lead sponsor	Universidad de Murcia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	prevention
Enrollment	10
Start date	1 June 2015
Primary completion	1 July 2015
Estimated completion	31 July 2015
Sites	1 location across Spain

Drugs / interventions tested

• Food Timing

Conditions studied

• Healthy Women — all drugs for Healthy Women →

Sponsor

Universidad de Murcia — full company profile →

Who can join

Adults 20 to 25, female only, with Healthy Women. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this investigation is to test the hypothesis that in humans, eating late may induce changes in saliva microbiota daily rhythms towards a more obesogenic and a less responsiveness to dietary treatments profile. These changes in microbiota may partly explain the weight loss difficulties that characterized late eaters in previous studies. Thus, the aim is to analyze the effect of the timing of food intake in humans' saliva microbiome daily rhythms in a randomized, crossover interventional study, in order to achieve.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Timing of food intake impacts daily rhythms of human salivary microbiota: a randomized, crossover study.
   Collado MC, Engen PA, Bandín C, Cabrera-Rubio R, et al · · 2018 · cited 77× · PMID 29233857 · DOI 10.1096/fj.201700697rr