NCT06746220 (AP-Pro-Fem) is a NA clinical trial of Microbiota sample in Healthy Women, sponsored by Centre Hospitalier Régional d'Orléans.

Who is sponsoring NCT06746220?

NCT06746220 is sponsored by Centre Hospitalier Régional d'Orléans.

What drugs are being tested in NCT06746220?

Interventions in NCT06746220: Microbiota sample, Salivary sample, Quality of life questionnaires, Nutritional evaluation, Assessment of physical health, Physical activity, Treatment with placebo or probiotic.

What condition does NCT06746220 study?

NCT06746220 studies Healthy Women.

Is NCT06746220 still recruiting?

NCT06746220 is currently recruiting now. Last updated 30 December 2025.

Last reviewed 2025-12-30 · How we verify

NCT06746220: AP-Pro-Fem

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Physical Activity and/or Probiotics on Body Composition and Physiological Parameters in Women

Recruiting now NA Last updated 30 December 2025

What this trial tests

NA trial testing Microbiota sample in Healthy Women in 120 participants. Currently enrolling.

Timeline

16 September 2024

Primary endpoint
15 September 2027

15 December 2027

Quick facts

Lead sponsor	Centre Hospitalier Régional d'Orléans
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	other
Enrollment	120
Start date	16 September 2024
Primary completion	15 September 2027
Estimated completion	15 December 2027
Sites	1 location across France

Drugs / interventions tested

Microbiota sample
Salivary sample — full drug profile →
Quality of life questionnaires
Nutritional evaluation
Assessment of physical health
Physical activity
Treatment with placebo or probiotic

Conditions studied

Healthy Women — all drugs for Healthy Women →

Sponsor

Centre Hospitalier Régional d'Orléans

Who can join

18 and older, female only, with Healthy Women. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective, comparative, double-blind, randomized, monocentric study. The objective of this project is to evaluate the effects on health of probiotic supplementation (PS) with or without physical activity (PA). Participants who meet the study criteria will be randomized into 4 groups: probiotic and physical activity group (A+), probiotic and non-physical activity group (A-), placebo and physical activity group (T+), placebo and non-physical activity group (T-). The probiotics used are Lactibiane® Reference provided by Pileje Laboratory. The study population are healthy women (university students) who do not practice sports. A total of 120 participants will participate. At inclusion, each participant will undergo a medical examination, collect microbiota and salivary samples and perform different tests (questionnaires, assessments of strength and endurance). Then, a follow up phase will last 6 weeks. Each participant will receive a pillbox containing capsules (probiotic or placebo in a double-blind manner). Participants which randomized in the PA groups (A+ and A-) will perform 2 physical activity sessions per week for 6 weeks. At the end of this follow up phase, tests conducting during inclusion will be performed again.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Healthy Women

Currently open trials in the same condition.

NCT07363421 — TMS-Induced LH Response in Healthy Women in Luteal Phase · NA · recruiting
NCT07515417 — Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults · NA · active not recruiting
NCT07439458 — Tumour Cell Response to Acute Aerobic Exercise in Breast Cancer Survivors: Modulatory Effects of Exercise Type and Inten · NA · recruiting
NCT04143659 — A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception · Phase 1 · active not recruiting

Other Centre Hospitalier Régional d'Orléans trials

Trials by the same sponsor.

NCT07522307 — Psychological Impact of an 80-km Ultra-Endurance Race · recruiting
NCT07522333 — Psychological Impact of an 120-km Ultra-Endurance Race · recruiting
NCT07334964 — Ultrasound-Guided Carpal Tunnel Infiltration: Comparison Between the Manual Method and a Robot-Assisted Method · NA · recruiting
NCT07203807 — Study of the Optimal Number of Repetitions to Investigate the Cerebral Activity by fNIRS During a Voluntary Movement and · completed
NCT07305701 — Cohort Study on Medical Students' Mental Health · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06746220 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Régional d'Orléans
Last refreshed: 30 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06746220.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing