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NCT03140540: VTI SVV
TEE as a Guide for Fluid Optimization in Major Abdominal Oncosurgery
NA trial testing TEE guided fluid therapy will be administered in Fluid Therapy in 60 participants. Completed in 27 February 2020.
27 February 2020
Quick facts
| Lead sponsor | Rajiv Gandhi Cancer Institute & Research Center, India |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 60 |
| Start date | 16 February 2019 |
| Primary completion | 27 February 2020 |
| Estimated completion | 27 February 2020 |
| Sites | 1 location across India |
Drugs / interventions tested
- TEE guided fluid therapy will be administered
- Stroke volume variation guided intravenous fluid.
Conditions studied
- Fluid Therapy — all drugs for Fluid Therapy →
Sponsor
Rajiv Gandhi Cancer Institute & Research Center, India
Who can join
Adults 18 to 80, any sex, with Fluid Therapy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Transesophageal echocardiography (TEE) as guide for tailoring perioperative fluid therapy to achieve individualized hemodynamic endpoint, target hemodynamic goals of stroke volume index (SVI) greater than 35 mL/m2 and cardiac index greater than 2.5 L/min/m2 and tissue oxygen delivery. Lactate levels as a surrogate indicator of organ perfusion as measured by arterial blood gas analysis intraoperatively, after 12 hours and 48 hrs postoperatively
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03140540
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Fluid Therapy
Currently open trials in the same condition.
- NCT07260890 — Paired Comparison of SVV and PVI Accuracy · recruiting
- NCT07522580 — Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children · recruiting
- NCT07255469 — Metabolic Fluid Responsiveness in Children · recruiting
- NCT06396884 — Hemodynamic Optimization During Spinal Anesthesia in the Elderly · recruiting
- NCT06206434 — Point of Care Ultrasound and Co-loading in Patients With Spinal-induced Hypotension and Cardiac Diseases · recruiting
Other Rajiv Gandhi Cancer Institute & Research Center, India trials
Trials by the same sponsor.
- NCT07258797 — Short Course or Long Course Radiotherapy as Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer · NA · not yet recruiting
- NCT06026475 — Role of Goal Directed Fluid Therapy in Enhanced Recovery After Surgery in Gastro-intestinal Oncosurgeries · NA · completed
- NCT05439109 — Correct Endotracheal Tube Placement Using Topographical Landmarks · NA · unknown
- NCT05721391 — Impact of Frailty on Postoperative Complications in Oncosurgery · completed
- NCT05142163 — Stroke Volume Variation and Plethysmography Variability Index as Goal Directed Fluid Therapy in Major Oncosurgeries · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03140540 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rajiv Gandhi Cancer Institute & Research Center, India
- Last refreshed: 26 October 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03140540.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing