NCT03139877 is a clinical trial in Pediatric Obesity, sponsored by Duke University.

Who is sponsoring NCT03139877?

NCT03139877 is sponsored by Duke University.

What condition does NCT03139877 study?

NCT03139877 studies Pediatric Obesity.

Is NCT03139877 still recruiting?

NCT03139877 is currently completed. Last updated 18 June 2021.

Last reviewed 2021-06-18 · How we verify

NCT03139877

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pediatric Obesity Observational Prospective Trial

Completed Last updated 18 June 2021

What this trial tests

trial in Pediatric Obesity in 295 participants. Completed in 7 January 2020.

Timeline

13 September 2016

Primary endpoint
7 January 2020

7 January 2020

Quick facts

Lead sponsor	Duke University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	295
Start date	13 September 2016
Primary completion	7 January 2020
Estimated completion	7 January 2020
Sites	1 location across United States

Conditions studied

Pediatric Obesity — all drugs for Pediatric Obesity →

Sponsor

Duke University

Who can join

Adults 10 to 18, any sex, with Pediatric Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Using an observational case-control cohort design, the investigator aims to define the mechanisms underlying microbiome regulation of metabolism in adolescence before and after medically indicated therapies for obesity. The investigator's overarching hypothesis is that gut bacteria control host weight, insulin sensitivity, and response to weight-loss treatments by modifying host metabolism.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

The Pediatric Obesity Microbiome and Metabolism Study (POMMS): Methods, Baseline Data, and Early Insights.
McCann JR, Bihlmeyer NA, Roche K, Catherine C, et al · · 2021 · cited 27× · PMID 33624438 · DOI 10.1002/oby.23081
Advanced Obesity Treatment Selection among Adolescents in a Pediatric Weight Management Program.
Suarez L, Skinner AC, Truong T, McCann JR, et al · · 2022 · cited 4× · PMID 34757829 · DOI 10.1089/chi.2021.0190
Branched chain amino acid metabolism and microbiome in adolescents with obesity during weight loss therapy
McCann JR, Yang C, Bihlmeyer NA, Tang R, et al · · 2025 · DOI 10.1101/2025.02.03.25321363
The Pediatric Obesity Microbiome and Metabolism Study (POMMS): Methods, Baseline Data, and Early Insights
McCann JR, Bihlmeyer NA, Roche K, Catherine C, et al · · 2020 · DOI 10.1101/2020.06.09.20126763

Verify or expand the search:

Other recruiting trials for Pediatric Obesity

Currently open trials in the same condition.

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NCT07229508 — Developmental Trajectories of Reinforcer Pathology and Childhood Obesity · recruiting
NCT06572345 — Low EnerGy DiEt iN Adolescents With Obesity and Type 2 Diabetes: The LEGEND Study · NA · recruiting

Other Duke University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03139877 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Duke University
Last refreshed: 18 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03139877.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing