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NCT03089814
Changes in Tissue Microcirculation During Ischemic Conditioning: Pilot Study
NA trial testing ischemic conditioning in Microcirculation in 20 participants. Completed in 10 July 2017.
10 July 2017
Quick facts
| Lead sponsor | Seoul National University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | diagnostic |
| Enrollment | 20 |
| Start date | 23 March 2017 |
| Primary completion | 10 July 2017 |
| Estimated completion | 10 July 2017 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- ischemic conditioning
Conditions studied
- Microcirculation — all drugs for Microcirculation →
Sponsor
Seoul National University Hospital
Who can join
Adults 20 to 80, any sex, with Microcirculation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Changes in tissue microcirculation during ischemic conditioning (4 cycles of 5-min ischemia and 5-min reperfusion) has not been well documented. In previous studies, there was difference in changes in microcirculation, such as recovery slope and occlusion slope, between healthy subjects and cardiac surgery patients. Moreover, the occlusion slope, which reflects local tissue oxygen consumption during ischemic period, is anticipated to decrease during repeated ischemia-reperfusion cycle by its protecting effect, however there has not been well-conducted study. The purpose of the study is to evaluate the changes in microcirculation measured by tissue oxygen saturation during ischemic conditioning between healthy volunteers and cardiac surgery patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of ischaemic conditioning on tissue oxygen saturation and heart rate variability: an observational study.
Cho YJ, Lee HC, Choi EK, Park S, et al · · 2019 · cited 2× · PMID 31154876 · DOI 10.1177/0300060519851656
Verify or expand the search:
- PubMed search for NCT03089814
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Seoul National University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03089814 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
- Last refreshed: 28 February 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03089814.
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