NCT03089762 is a Phase 1 clinical trial of Intra-articular injection of SVF plus PRP in Osteoarthritis, sponsored by Bioheart, Inc..

Who is sponsoring NCT03089762?

NCT03089762 is sponsored by Bioheart, Inc..

What drugs are being tested in NCT03089762?

Interventions in NCT03089762: Intra-articular injection of SVF plus PRP.

What condition does NCT03089762 study?

NCT03089762 studies Osteoarthritis.

Is NCT03089762 still recruiting?

NCT03089762 is currently completed. Last updated 27 March 2017.

Last reviewed 2017-03-27 · How we verify

NCT03089762

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intra-articular Injection in the Knee of Adipose Derived Stromal Cells and Platelet Rich Plasma for Osteoarthritis

Completed Phase 1 Last updated 27 March 2017

What this trial tests

Phase 1 trial testing Intra-articular injection of SVF plus PRP in Osteoarthritis in 10 participants. Completed in 30 December 2014.

Timeline

12 February 2012

Primary endpoint
30 December 2014

30 December 2014

Quick facts

Lead sponsor	Bioheart, Inc.
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	10
Start date	12 February 2012
Primary completion	30 December 2014
Estimated completion	30 December 2014

Drugs / interventions tested

Intra-articular injection of SVF plus PRP — full drug profile →

Conditions studied

Osteoarthritis — all drugs for Osteoarthritis →

Sponsor

Bioheart, Inc. — full company profile →

Who can join

50 and older, any sex, with Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Stromal vascular fraction (SVF) can easily be obtained from a mini-lipoaspirate procedure of fat tissue and platelet rich plasma (PRP) can be obtained from peripheral blood. Evaluated the safety and preliminary efficacy of administering SVF and PRP intra-articularly into patients with osteoarthritis grade 1 and 2.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Injective mesenchymal stem cell-based treatments for knee osteoarthritis: from mechanisms of action to current clinical evidences.
Lopa S, Colombini A, Moretti M, de Girolamo L. · · 2019 · cited 116× · PMID 30159741 · DOI 10.1007/s00167-018-5118-9
Intra-articular injection in the knee of adipose derived stromal cells (stromal vascular fraction) and platelet rich plasma for osteoarthritis.
Bansal H, Comella K, Leon J, Verma P, et al · · 2017 · cited 81× · PMID 28629466 · DOI 10.1186/s12967-017-1242-4
Minimally Manipulated Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Systematic Review of Clinical Evidence.
Di Matteo B, Vandenbulcke F, Vitale ND, Iacono F, et al · · 2019 · cited 67× · PMID 31485234 · DOI 10.1155/2019/1735242

Verify or expand the search:

Other recruiting trials for Osteoarthritis

Currently open trials in the same condition.

NCT07404891 — Clinical Trial on the Efficacy and Safety of ALT001 in Osteoarthritis · NA · recruiting
NCT07118501 — A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System · recruiting
NCT06631638 — EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN)) · NA · recruiting
NCT07198750 — "Bimodal vs Unimodal High-Intensity Pulsed Electromagnetic Field Therapy in Older Adults With Knee Osteoarthritis" · NA · recruiting
NCT07006714 — Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA) · Phase 4 · active not recruiting

Other Bioheart, Inc. trials

Trials by the same sponsor.

NCT03226093 — Safety Analysis of Implantation of Stromal Vascular Fraction · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03089762 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Bioheart, Inc.
Last refreshed: 27 March 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03089762.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing