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NCT03072927
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
trial testing MILD in Lumbar Spinal Stenosis in 8,000 participants. Currently enrolling.
1 December 2026
Quick facts
| Lead sponsor | Stryker Instruments |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 8,000 |
| Start date | 10 March 2017 |
| Primary completion | 1 December 2026 |
| Estimated completion | 1 December 2026 |
| Sites | 2270 locations across United States |
Drugs / interventions tested
- MILD
- Interspinous Process Decompression
Conditions studied
- Lumbar Spinal Stenosis — all drugs for Lumbar Spinal Stenosis →
Sponsor
Stryker Instruments — full company profile →
Who can join
18 and older, any sex, with Lumbar Spinal Stenosis. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Rate of participants with harms associated with the index procedure
Time frame: 24 months
Rate of participants with harms associated with the index procedure including, but not limited to, revisions, displacement, mechanical complications, and death. Complications will be counted if they are recorded during the index hospitalization, or any rehospitalization within 30 days of discharge. -
Rate of surgical, minimally invasive intervention.
Time frame: 24 months
Measure the rate of Medicare beneficiary surgical and minimally invasive intervention for LSS with NC post index procedure.
Sponsor's own description
This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months post-treatment with MILD, tested against a control group of similar patients that have had a comparable procedure. This study will start with patients treated with a study procedure having an index date on or after January 1, 2017, and enrollment will continue until stopped by the sponsor.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03072927
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lumbar Spinal Stenosis
Currently open trials in the same condition.
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- NCT07233798 — Presence of Dural Pulsation in Patients Diagnosed With Lumbar Spinal Stenosis · recruiting
- NCT07281625 — Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis · EARLY_PHASE1 · recruiting
- NCT07001982 — Lumbar Spinal Stenosis and Central Sensitization · recruiting
- NCT06959355 — Frailty and Associated Factors in Lumbar Spinal Stenosis · recruiting
Other Stryker Instruments trials
Trials by the same sponsor.
- NCT07392333 — Prospective Study of Basivertebral Nerve Ablation With the OptaBlate BVN System for Vertebrogenic Low Back Pain · not yet recruiting
- NCT04154605 — ClariFix Rhinitis RCT · NA · completed
- NCT04795765 — SpineJack System Postmarket Registry · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03072927 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Stryker Instruments
- Last refreshed: 3 June 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03072927.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing