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NCT07281625
Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis
EARLY_PHASE1 trial testing Decompressive Laminectomy in Lumbar Spinal Stenosis in 60 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Punjab Health Care Commission |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 October 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Decompressive Laminectomy
- Decompressive Laminectomy With Transpedicular Screw Fixation
Conditions studied
- Lumbar Spinal Stenosis — all drugs for Lumbar Spinal Stenosis →
Sponsor
Punjab Health Care Commission
Who can join
Adults 30 to 60, any sex, with Lumbar Spinal Stenosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lumbar spinal stenosis is a condition where the spinal canal becomes narrowed and can cause symptoms such as back pain, numbness, leg pain, and difficulty walking. Surgery is often considered when symptoms do not improve with medical treatment. This study will compare two types of surgery used to treat lumbar spinal stenosis: decompressive laminectomy alone and decompressive laminectomy with transpedicular screw fixation. Patients will be randomly assigned to one of the two surgical options. The purpose of this study is to determine which approach provides better pain relief, improved function, fewer complications, and better spinal stability after surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07281625
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lumbar Spinal Stenosis
Currently open trials in the same condition.
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- NCT07233798 — Presence of Dural Pulsation in Patients Diagnosed With Lumbar Spinal Stenosis · recruiting
- NCT07001982 — Lumbar Spinal Stenosis and Central Sensitization · recruiting
- NCT06959355 — Frailty and Associated Factors in Lumbar Spinal Stenosis · recruiting
- NCT06719037 — Comparision of Endoscopic Discectomy and Microdiscectomy for the Treatment of Lumbar Spinal Stenosis · NA · recruiting
Other Punjab Health Care Commission trials
Trials by the same sponsor.
- NCT07281612 — Hand-made Extracorporeal Knotting Versus Clip for Stump Closure in Laparoscopic Appendectomy · EARLY_PHASE1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07281625 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Punjab Health Care Commission
- Last refreshed: 15 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07281625.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing