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NCT03046576
Prognostic Value of Plasma DPP4 Activity in ST-elevation Myocardial Infarction Patients
trial testing plasma DPP4 activity in Coronary Angiography in 625 participants. Completed in 30 September 2015.
30 September 2015
Quick facts
| Lead sponsor | Chinese PLA General Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 625 |
| Start date | 1 January 2013 |
| Primary completion | 30 September 2015 |
| Estimated completion | 30 September 2015 |
Drugs / interventions tested
- plasma DPP4 activity
Conditions studied
- Coronary Angiography — all drugs for Coronary Angiography →
- Dipeptidyl Peptidase 4 — all drugs for Dipeptidyl Peptidase 4 →
Sponsor
Chinese PLA General Hospital
Who can join
18 and older, any sex, with Coronary Angiography or Dipeptidyl Peptidase 4. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Increased plasma DPP4 activity (DPP4a) could predict both subclinical and new-onset atherosclerosis, and our previous study has found that the DPP4a was significantly lower in MI patients compared with patients having chest pain or unstable angina alone, and DPP4a is associated with no-reflow and major bleeding events in STEMI patients during hospital stay. As no-reflow phenomenon and major bleeding events independently associates with a worse in-hospital and long-term prognosis. One may speculate that the DPP4a is associated with long-term follow-up adverse cardiovascular events in these patients.The hypothesis was tested in this study.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Prognostic value of plasma DPP4 activity in ST-elevation myocardial infarction.
Li JW, Chen YD, Chen WR, You Q, et al · · 2017 · cited 5× · PMID 28587613 · DOI 10.1186/s12933-017-0553-3
Verify or expand the search:
- PubMed search for NCT03046576
- Europe PMC full search
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Other Chinese PLA General Hospital trials
Trials by the same sponsor.
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- NCT07494981 — Individualized Precision Therapy With Ceftazidime and Avibactam Guided by PK/PD in Geriatric Populations · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03046576 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chinese PLA General Hospital
- Last refreshed: 21 July 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03046576.
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