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NCT03042442: CDNPAN

Relation Between Cachexia, Diabetes and periNeural Invasion in PANcreatic Cancer- Biomarkers Substudy

Completed Last updated 19 March 2019
What this trial tests

trial testing Point-of care biomarkers in Pancreatic Cancer, Adult in 114 participants. Completed in 30 September 2018.

Timeline
1 January 2017
Primary endpoint
30 June 2018
30 September 2018

Quick facts

Lead sponsorIuliu Hatieganu University of Medicine and Pharmacy
StatusCompleted
Study typeOBSERVATIONAL
Enrollment114
Start date1 January 2017
Primary completion30 June 2018
Estimated completion30 September 2018
Sites1 location across Romania

Drugs / interventions tested

Conditions studied

Sponsor

Iuliu Hatieganu University of Medicine and Pharmacy

Who can join

Adults 18 to 100, any sex, with Pancreatic Cancer, Adult or Cachexia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine the interrelationship between cachexia, neural invasion and diabetes in patients with pancreatic cancer. Thus the investigators propose to identify the protein expression levels of Activin and Midkine in plasma of patients with different stages of pancreatic adenocarcinoma compared with healthy patients and to evaluate the possible correlation with diabetes, tumor size and tumor stage.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Relationship between cachexia and perineural invasion in pancreatic adenocarcinoma.
    Petrusel L, Rusu I, Leucuta DC, Seicean R, et al · · 2019 · cited 6× · PMID 31908718 · DOI 10.4251/wjgo.v11.i12.1126
  2. Perineural Invasion in Pancreatic Ductal Adenocarcinoma: Recapitulating Its Importance and Defining Future Directions.
    Lovecek M, Dirimtekin E, Garajová I, Gasparini G, et al · · 2025 · cited 2× · PMID 40981722 · DOI 10.1002/ueg2.70118

Verify or expand the search:

Other recruiting trials for Pancreatic Cancer, Adult

Currently open trials in the same condition.

Other Iuliu Hatieganu University of Medicine and Pharmacy trials

Trials by the same sponsor.

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Data sources for this page

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